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Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines. / Naikhin, AN; Rudenko, LG; Arden, N; Katz, J; Grigoryeva, YP; Donina, SA; Desheva, YA; Rextin, AR; Cox, N.

In: Voprosy Virusologii, Vol. 43, No. 3, 1998, p. 130-134.

Research output: Contribution to journal › Article › peer-review

Harvard

Naikhin, AN, Rudenko, LG, Arden, N, Katz, J, Grigoryeva, YP, Donina, SA, Desheva, YA, Rextin, AR & Cox, N 1998, 'Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines', Voprosy Virusologii, vol. 43, no. 3, pp. 130-134.

APA

Naikhin, AN., Rudenko, LG., Arden, N., Katz, J., Grigoryeva, YP., Donina, SA., Desheva, YA., Rextin, AR., & Cox, N. (1998). Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines. Voprosy Virusologii, 43(3), 130-134.

Vancouver

Naikhin AN, Rudenko LG, Arden N, Katz J, Grigoryeva YP, Donina SA et al. Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines. Voprosy Virusologii. 1998;43(3):130-134.

Author

Naikhin, AN ; Rudenko, LG ; Arden, N ; Katz, J ; Grigoryeva, YP ; Donina, SA ; Desheva, YA ; Rextin, AR ; Cox, N. / Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines. In: Voprosy Virusologii. 1998 ; Vol. 43, No. 3. pp. 130-134.

BibTeX

@article{eb16d179fa08461981f204b942728b51,
title = "Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines",
abstract = "A total of 159 subjects aged 65-87 years were immunized with live cold-adapted reassortant influenza vaccine (CRIV), inactivated influenza vaccine (IIV), and with both vaccines (CRIV+IIV) one year, two and three years running. The frequency and intensity of accumulation of postvaccinal secretory and humoral antibodies in elderly subjects depend on the scheme of immunization and history of vaccinations. Combination of the two vaccines effectively stimulated both components of immunity and ensured a longer persistence of postvaccinal antibodies in high concentrations. Immunization with CRIV+IIV for three years resulted in a gradual increase of the intensity of prevaccination secretory and humoral immunity. Before the third seasonal immunization the majority (63-75%) of vaccinees had antibodies in protective titers.",
keywords = "influenza vaccines, elderly subjects, immunization schemes, immune response, COLD-ADAPTED INFLUENZA, A VIRUS-VACCINES, VACCINATION, ANTIBODIES, EFFICACY",
author = "AN Naikhin and LG Rudenko and N Arden and J Katz and YP Grigoryeva and SA Donina and YA Desheva and AR Rextin and N Cox",
year = "1998",
language = "не определен",
volume = "43",
pages = "130--134",
journal = "Вопросы вирусологии",
issn = "0507-4088",
publisher = "Медицина",
number = "3",

}

RIS

TY - JOUR

T1 - Relationship between immune response of elderly subjects and number of annual seasonal immunizations with live and inactivated influenza vaccines

AU - Naikhin, AN

AU - Rudenko, LG

AU - Arden, N

AU - Katz, J

AU - Grigoryeva, YP

AU - Donina, SA

AU - Desheva, YA

AU - Rextin, AR

AU - Cox, N

PY - 1998

Y1 - 1998

N2 - A total of 159 subjects aged 65-87 years were immunized with live cold-adapted reassortant influenza vaccine (CRIV), inactivated influenza vaccine (IIV), and with both vaccines (CRIV+IIV) one year, two and three years running. The frequency and intensity of accumulation of postvaccinal secretory and humoral antibodies in elderly subjects depend on the scheme of immunization and history of vaccinations. Combination of the two vaccines effectively stimulated both components of immunity and ensured a longer persistence of postvaccinal antibodies in high concentrations. Immunization with CRIV+IIV for three years resulted in a gradual increase of the intensity of prevaccination secretory and humoral immunity. Before the third seasonal immunization the majority (63-75%) of vaccinees had antibodies in protective titers.

AB - A total of 159 subjects aged 65-87 years were immunized with live cold-adapted reassortant influenza vaccine (CRIV), inactivated influenza vaccine (IIV), and with both vaccines (CRIV+IIV) one year, two and three years running. The frequency and intensity of accumulation of postvaccinal secretory and humoral antibodies in elderly subjects depend on the scheme of immunization and history of vaccinations. Combination of the two vaccines effectively stimulated both components of immunity and ensured a longer persistence of postvaccinal antibodies in high concentrations. Immunization with CRIV+IIV for three years resulted in a gradual increase of the intensity of prevaccination secretory and humoral immunity. Before the third seasonal immunization the majority (63-75%) of vaccinees had antibodies in protective titers.

KW - influenza vaccines

KW - elderly subjects

KW - immunization schemes

KW - immune response

KW - COLD-ADAPTED INFLUENZA

KW - A VIRUS-VACCINES

KW - VACCINATION

KW - ANTIBODIES

KW - EFFICACY

M3 - статья

VL - 43

SP - 130

EP - 134

JO - Вопросы вирусологии

JF - Вопросы вирусологии

SN - 0507-4088

IS - 3

ER -

ID: 61121365