Research output: Contribution to journal › Article › peer-review
Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves. / Whaley, A. K.; Ponkratova, A. O.; Serebryakov, E. B.; Smirnov, S. N.; Proksh, P.; Ionov, N. S.; Poroikov, V. V.; Luzhanin, V. G.
In: Pharmaceutical Chemistry Journal, Vol. 55, No. 3, 06.2021, p. 253-258.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Phytochemical Analysis of Polyphenol Secondary Metabolites in Cloudberry (Rubus Chamaemorus L.) Leaves
AU - Whaley, A. K.
AU - Ponkratova, A. O.
AU - Serebryakov, E. B.
AU - Smirnov, S. N.
AU - Proksh, P.
AU - Ionov, N. S.
AU - Poroikov, V. V.
AU - Luzhanin, V. G.
N1 - Publisher Copyright: © 2021, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2021/6
Y1 - 2021/6
N2 - Phytochemical analysis of cloudberry leaves isolated one new (1) and four well-known compounds (2-5) and established their structures. Compounds 1 (4-O-alpha-L-arabinofuranosylellagic acid) and 2 [(-)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavonoid glucuronic glycosides quercetin 3-O-beta-D-glucuronide (3), quercetin 3-O-beta-D-2 ''-galloylglucuronide (4), and kaempferol 3-O-beta-D-glucuronide (5). Compounds 4 and 5 were isolated from Rubus chamaemorus L. for the first time. Predictions of the biological activity spectra for isolated 1-5 using the PASS program provided insights regarding the most promising directions for studying their biological activity.
AB - Phytochemical analysis of cloudberry leaves isolated one new (1) and four well-known compounds (2-5) and established their structures. Compounds 1 (4-O-alpha-L-arabinofuranosylellagic acid) and 2 [(-)-epicatechin] belonged to the tannin class. The rest of the isolated compounds were the flavonoid glucuronic glycosides quercetin 3-O-beta-D-glucuronide (3), quercetin 3-O-beta-D-2 ''-galloylglucuronide (4), and kaempferol 3-O-beta-D-glucuronide (5). Compounds 4 and 5 were isolated from Rubus chamaemorus L. for the first time. Predictions of the biological activity spectra for isolated 1-5 using the PASS program provided insights regarding the most promising directions for studying their biological activity.
KW - biological activity
KW - flavonoid glucuronide glycosides
KW - in silico estimation
KW - individual substances
KW - PASS
KW - polyphenols
KW - Rubus chamaemorus
KW - tannins
KW - PHENOLIC-COMPOUNDS
UR - http://www.scopus.com/inward/record.url?scp=85108006483&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/442fb9af-3371-317d-ae6c-f4919fa2470a/
U2 - 10.1007/s11094-021-02407-y
DO - 10.1007/s11094-021-02407-y
M3 - Article
AN - SCOPUS:85108006483
VL - 55
SP - 253
EP - 258
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 3
ER -
ID: 86099109