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Palladium(II)-Stabilized Pyridine-2-Diazotates : Synthesis, Structural Characterization, and Cytotoxicity Studies. / Tskhovrebov, Alexander G.; Vasileva, Anna A.; Goddard, Richard; Riedel, Tina; Dyson, Paul J.; Mikhaylov, Vladimir N.; Serebryanskaya, Tatiyana V.; Sorokoumov, Viktor N.; Haukka, Matti.

In: Inorganic Chemistry, Vol. 57, No. 3, 05.02.2018, p. 930-934.

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Tskhovrebov, Alexander G. ; Vasileva, Anna A. ; Goddard, Richard ; Riedel, Tina ; Dyson, Paul J. ; Mikhaylov, Vladimir N. ; Serebryanskaya, Tatiyana V. ; Sorokoumov, Viktor N. ; Haukka, Matti. / Palladium(II)-Stabilized Pyridine-2-Diazotates : Synthesis, Structural Characterization, and Cytotoxicity Studies. In: Inorganic Chemistry. 2018 ; Vol. 57, No. 3. pp. 930-934.

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@article{d29c058c15e3475e998dbd67474dabbc,
title = "Palladium(II)-Stabilized Pyridine-2-Diazotates: Synthesis, Structural Characterization, and Cytotoxicity Studies",
abstract = "Well-defined diazotates are scarce. Here we report the synthesis of unprecedented homoleptic palladium(II) diazotate complexes. The palladium(II)-mediated nitrosylation of 2-aminopyridines with NaNO2 results in the formation of metal-stabilized diazotates, which were found to be cytotoxic to human ovarian cancer cells.",
author = "Tskhovrebov, {Alexander G.} and Vasileva, {Anna A.} and Richard Goddard and Tina Riedel and Dyson, {Paul J.} and Mikhaylov, {Vladimir N.} and Serebryanskaya, {Tatiyana V.} and Sorokoumov, {Viktor N.} and Matti Haukka",
note = "Funding Information: This work was supported by the Ministry of Education of the RF (Grant MK-676.2017.3) and RFBR (Grant 17-53-04050). M.H. thanks the Academy of Finland (Project 295581) for financial support. Funding Information: We thank Galina L. Starova for her assistance with X-ray crystallography. A.G.T. is grateful to Prof. Alois F{\"u}rstner at MPI f{\"u}r Kohlenforschung for providing a fruitful research environment. This work was supported by the Ministry of Education of the RF (Grant MK-676.2017.3) and RFBR (Grant 17-53-04050). M.H. thanks the Academy of Finland (Project 295581) for financial support. Publisher Copyright: {\textcopyright} 2018 American Chemical Society. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",
year = "2018",
month = feb,
day = "5",
doi = "10.1021/acs.inorgchem.8b00072",
language = "English",
volume = "57",
pages = "930--934",
journal = "Inorganic Chemistry",
issn = "0020-1669",
publisher = "American Chemical Society",
number = "3",

}

RIS

TY - JOUR

T1 - Palladium(II)-Stabilized Pyridine-2-Diazotates

T2 - Synthesis, Structural Characterization, and Cytotoxicity Studies

AU - Tskhovrebov, Alexander G.

AU - Vasileva, Anna A.

AU - Goddard, Richard

AU - Riedel, Tina

AU - Dyson, Paul J.

AU - Mikhaylov, Vladimir N.

AU - Serebryanskaya, Tatiyana V.

AU - Sorokoumov, Viktor N.

AU - Haukka, Matti

N1 - Funding Information: This work was supported by the Ministry of Education of the RF (Grant MK-676.2017.3) and RFBR (Grant 17-53-04050). M.H. thanks the Academy of Finland (Project 295581) for financial support. Funding Information: We thank Galina L. Starova for her assistance with X-ray crystallography. A.G.T. is grateful to Prof. Alois Fürstner at MPI für Kohlenforschung for providing a fruitful research environment. This work was supported by the Ministry of Education of the RF (Grant MK-676.2017.3) and RFBR (Grant 17-53-04050). M.H. thanks the Academy of Finland (Project 295581) for financial support. Publisher Copyright: © 2018 American Chemical Society. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 2018/2/5

Y1 - 2018/2/5

N2 - Well-defined diazotates are scarce. Here we report the synthesis of unprecedented homoleptic palladium(II) diazotate complexes. The palladium(II)-mediated nitrosylation of 2-aminopyridines with NaNO2 results in the formation of metal-stabilized diazotates, which were found to be cytotoxic to human ovarian cancer cells.

AB - Well-defined diazotates are scarce. Here we report the synthesis of unprecedented homoleptic palladium(II) diazotate complexes. The palladium(II)-mediated nitrosylation of 2-aminopyridines with NaNO2 results in the formation of metal-stabilized diazotates, which were found to be cytotoxic to human ovarian cancer cells.

UR - http://www.scopus.com/inward/record.url?scp=85041653998&partnerID=8YFLogxK

U2 - 10.1021/acs.inorgchem.8b00072

DO - 10.1021/acs.inorgchem.8b00072

M3 - Article

C2 - 29356518

AN - SCOPUS:85041653998

VL - 57

SP - 930

EP - 934

JO - Inorganic Chemistry

JF - Inorganic Chemistry

SN - 0020-1669

IS - 3

ER -

ID: 32723479