Myxopapillary Ependymoma of Lumbar Soft Tissue: A Case Report With Gene Expression Evaluation

Ksenya V. Shelekhova, Vitaly V. Egorenkov, Valery A. Kheinstein, Anastasia M. Konstantinova, Aglaya Iyevleva, Evgeny N. Imyanitov, Marina V. Matsko, Dmitry E. Matsko

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Primary extraspinal myxopapillary ependymoma (MPE) is an exceptionally rare lesion that is mainly located in the subcutaneous sacrococcygeal region. We describe the first case of MPE that presented as an intramuscular tumor mass located in the lumbar area. Absence of the visible connection with the spinal cord and lack of any other tumors in the reported case argue for the primary ectopic origin of the MPE. The differential diagnosis of MPE is discussed. Additionally, we evaluated the expression level of molecular biomarkers that have a prognostic value in central nervous system tumors.

Original languageEnglish
Pages (from-to)364-369
Number of pages6
JournalInternational Journal of Surgical Pathology
Volume26
Issue number4
DOIs
StatePublished - 1 Jun 2018

Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine

Keywords

  • ectopic
  • extraspinal
  • gene expression
  • lumbar
  • myxopapillary ependymoma
  • soft tissue

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