Monolithic methacrylate polymeric sorbents: Development of methods for chemical modification of the surface for the subsequent bioaffine functionalization

Research output

5 Citations (Scopus)

Abstract

Copolymers containing aldehyde, succinimidyl carbonate, and imidazolecarbamate groups were prepared by polymer-analogous transformations of epoxy groups of a macroporous monolithic polymeric support derived from glycidyl methacrylate and ethylene glycol dimethacyrlate. The effect of certain parameters on the course of the copolymer modification and immobilization of a protein on the surface of the polymeric support was studied. The possibility of using the matrices obtained for development of biorecognizing systems was examined.

Original languageEnglish
Pages (from-to)1403-1409
Number of pages7
JournalRussian Journal of Applied Chemistry
Volume81
Issue number8
DOIs
Publication statusPublished - 1 Aug 2008

Fingerprint

Methacrylates
Chemical modification
Sorbents
Copolymers
Ethylene Glycol
Ethylene glycol
Aldehydes
Carbonates
Polymers
Proteins
succinimidyl carbonate
glycidyl methacrylate

Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

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author = "Sinitsyna, {E. S.} and Vlasova, {E. N.} and Vlakh, {E. G.} and Tennikova, {T. B.}",
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AU - Sinitsyna, E. S.

AU - Vlasova, E. N.

AU - Vlakh, E. G.

AU - Tennikova, T. B.

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AB - Copolymers containing aldehyde, succinimidyl carbonate, and imidazolecarbamate groups were prepared by polymer-analogous transformations of epoxy groups of a macroporous monolithic polymeric support derived from glycidyl methacrylate and ethylene glycol dimethacyrlate. The effect of certain parameters on the course of the copolymer modification and immobilization of a protein on the surface of the polymeric support was studied. The possibility of using the matrices obtained for development of biorecognizing systems was examined.

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