Induction of antimicrobial peptide synthesis by the fat body cells of maggots of Calliphora vicina R.-D. (Diptera, Calliphoridae)

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2 Scopus citations

Abstract

Fat body is the major site of peptide antibiotic synthesis in insects. The goal of this work was to search in Calliphora vicina maggot for humoral factors that induce synthesis of antimicrobial peptides by the fat body cells in trauma. The preliminary analysis has shown that the activation factor revealed in hemolymph is a thermostable hydrophilic compound with a molecular mass lower than 3 kDa. The integument epitheliocytes were also found to release the humoral factors directly stimulating synthesis of antimicrobial peptides by the fat body.

Original languageEnglish
Pages (from-to)543-551
Number of pages9
JournalJournal of Evolutionary Biochemistry and Physiology
Volume47
Issue number6
DOIs
StatePublished - 1 Dec 2011

Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry
  • Physiology

Keywords

  • antimicrobial peptides
  • fat body
  • hemocytes
  • insect immunity
  • integuments
  • Spaetzle

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