Standard

Immunopathological syndromes: state of the art. / Кудлай, Дмитрий Анатольевич; Козлов, В.Г.; Савченко , А.А.; СИМБИРЦЕВ , А.С.; Анисимова, Е.Е.; Кудрявцев, Игорь Владимирович; Кульпина, Анастасия Ярославовна; Рубинштейн, Артем Аркадьевич; Рябкова, Варвара Александровна; Чурилов, Леонид Павлович; Сироткина, О.В.; Вавилова, Татьяна Владимировна; Старшинова, Анна Андреевна; Борисов, А.Г.

In: Frontiers of Medicine, Vol. 12, 1633624, 13.08.2025.

Research output: Contribution to journal › Review article › peer-review

Harvard

Кудлай, ДА, Козлов, ВГ, Савченко , АА, СИМБИРЦЕВ , АС, Анисимова, ЕЕ, Кудрявцев, ИВ, Кульпина, АЯ, Рубинштейн, АА, Рябкова, ВА, Чурилов, ЛП, Сироткина, ОВ, Вавилова, ТВ, Старшинова, АА & Борисов, АГ 2025, 'Immunopathological syndromes: state of the art.', Frontiers of Medicine, vol. 12, 1633624. https://doi.org/10.3389/fmed.2025.1633624

APA

Кудлай, Д. А., Козлов, В. Г., Савченко , А. А., СИМБИРЦЕВ , А. С., Анисимова, Е. Е., Кудрявцев, И. В., Кульпина, А. Я., Рубинштейн, А. А., Рябкова, В. А., Чурилов, Л. П., Сироткина, О. В., Вавилова, Т. В., Старшинова, А. А., & Борисов, А. Г. (2025). Immunopathological syndromes: state of the art. Frontiers of Medicine, 12, [1633624]. https://doi.org/10.3389/fmed.2025.1633624

Vancouver

Кудлай ДА, Козлов ВГ, Савченко АА, СИМБИРЦЕВ  АС, Анисимова ЕЕ, Кудрявцев ИВ et al. Immunopathological syndromes: state of the art. Frontiers of Medicine. 2025 Aug 13;12. 1633624. https://doi.org/10.3389/fmed.2025.1633624

Author

Кудлай, Дмитрий Анатольевич ; Козлов, В.Г. ; Савченко , А.А. ; СИМБИРЦЕВ , А.С. ; Анисимова, Е.Е. ; Кудрявцев, Игорь Владимирович ; Кульпина, Анастасия Ярославовна ; Рубинштейн, Артем Аркадьевич ; Рябкова, Варвара Александровна ; Чурилов, Леонид Павлович ; Сироткина, О.В. ; Вавилова, Татьяна Владимировна ; Старшинова, Анна Андреевна ; Борисов, А.Г. / Immunopathological syndromes: state of the art. In: Frontiers of Medicine. 2025 ; Vol. 12.

BibTeX

@article{9a674623b53a4f95970984956c186b74,
title = "Immunopathological syndromes: state of the art.",
abstract = "The review of the current state of knowledge on local and systemic immunopathological reactions of cellular and humoral origin, as well as the ways of their interaction, is considered in this article. This study aimed to organize, standardize, and conceptualize existing knowledge about immunopathological syndromes associated with innate immunity. It highlights syndromes linked to type I, II, and III hypersensitivity reactions, while also separately examining manifestations related to immunosuppression disorders. The review outlines how to differentiate humoral immunity syndromes based on the classes of immunoglobulins A, M, E, and the four subclasses of immunoglobulin G. Additionally, it provides a detailed analysis of complement system disorders and the mechanisms of systemic inflammatory response syndrome, as well as their role in various pathological processes. The authors advocate for a unified set of definitions for immunopathological syndromes related to adaptive immunity, aiming to develop a new concept of their pathogenesis. Currently, many definitions of these syndromes lack consensus, stemming from varying interpretations of their manifestations. The authors also propose standardized tools for assessing immunopathological syndromes, along with guidelines for staging and treatment optimization.",
keywords = "COVID-19, adaptive immunity, diagnostics of immune disorders, immune pathology, immune system, immunothrombosis",
author = "Кудлай, {Дмитрий Анатольевич} and В.Г. Козлов and А.А. Савченко and А.С. СИМБИРЦЕВ  and Е.Е. Анисимова and Кудрявцев, {Игорь Владимирович} and Кульпина, {Анастасия Ярославовна} and Рубинштейн, {Артем Аркадьевич} and Рябкова, {Варвара Александровна} and Чурилов, {Леонид Павлович} and О.В. Сироткина and Вавилова, {Татьяна Владимировна} and Старшинова, {Анна Андреевна} and А.Г. Борисов",
note = "Copyright {\textcopyright} 2025 Kudlay, Kozlov, Savchenko, Simbirtsev, Anisimova, Kudryavtsev, Kulpina, Rubinstein, Ryabkova, Churilov, Sirotkina, Vavilova, Starshinova and Borisov.",
year = "2025",
month = aug,
day = "13",
doi = "10.3389/fmed.2025.1633624",
language = "English",
volume = "12",
journal = "Frontiers of Medicine",
issn = "2095-0217",
publisher = "Springer Nature",

}

RIS

TY - JOUR

T1 - Immunopathological syndromes: state of the art.

AU - Кудлай, Дмитрий Анатольевич

AU - Козлов, В.Г.

AU - Савченко , А.А.

AU - СИМБИРЦЕВ , А.С.

AU - Анисимова, Е.Е.

AU - Кудрявцев, Игорь Владимирович

AU - Кульпина, Анастасия Ярославовна

AU - Рубинштейн, Артем Аркадьевич

AU - Рябкова, Варвара Александровна

AU - Чурилов, Леонид Павлович

AU - Сироткина, О.В.

AU - Вавилова, Татьяна Владимировна

AU - Старшинова, Анна Андреевна

AU - Борисов, А.Г.

N1 - Copyright © 2025 Kudlay, Kozlov, Savchenko, Simbirtsev, Anisimova, Kudryavtsev, Kulpina, Rubinstein, Ryabkova, Churilov, Sirotkina, Vavilova, Starshinova and Borisov.

PY - 2025/8/13

Y1 - 2025/8/13

N2 - The review of the current state of knowledge on local and systemic immunopathological reactions of cellular and humoral origin, as well as the ways of their interaction, is considered in this article. This study aimed to organize, standardize, and conceptualize existing knowledge about immunopathological syndromes associated with innate immunity. It highlights syndromes linked to type I, II, and III hypersensitivity reactions, while also separately examining manifestations related to immunosuppression disorders. The review outlines how to differentiate humoral immunity syndromes based on the classes of immunoglobulins A, M, E, and the four subclasses of immunoglobulin G. Additionally, it provides a detailed analysis of complement system disorders and the mechanisms of systemic inflammatory response syndrome, as well as their role in various pathological processes. The authors advocate for a unified set of definitions for immunopathological syndromes related to adaptive immunity, aiming to develop a new concept of their pathogenesis. Currently, many definitions of these syndromes lack consensus, stemming from varying interpretations of their manifestations. The authors also propose standardized tools for assessing immunopathological syndromes, along with guidelines for staging and treatment optimization.

AB - The review of the current state of knowledge on local and systemic immunopathological reactions of cellular and humoral origin, as well as the ways of their interaction, is considered in this article. This study aimed to organize, standardize, and conceptualize existing knowledge about immunopathological syndromes associated with innate immunity. It highlights syndromes linked to type I, II, and III hypersensitivity reactions, while also separately examining manifestations related to immunosuppression disorders. The review outlines how to differentiate humoral immunity syndromes based on the classes of immunoglobulins A, M, E, and the four subclasses of immunoglobulin G. Additionally, it provides a detailed analysis of complement system disorders and the mechanisms of systemic inflammatory response syndrome, as well as their role in various pathological processes. The authors advocate for a unified set of definitions for immunopathological syndromes related to adaptive immunity, aiming to develop a new concept of their pathogenesis. Currently, many definitions of these syndromes lack consensus, stemming from varying interpretations of their manifestations. The authors also propose standardized tools for assessing immunopathological syndromes, along with guidelines for staging and treatment optimization.

KW - COVID-19

KW - adaptive immunity

KW - diagnostics of immune disorders

KW - immune pathology

KW - immune system

KW - immunothrombosis

UR - https://www.mendeley.com/catalogue/f2223ef2-db69-3c05-a023-d997b1f7043b/

U2 - 10.3389/fmed.2025.1633624

DO - 10.3389/fmed.2025.1633624

M3 - Review article

C2 - 40880768

VL - 12

JO - Frontiers of Medicine

JF - Frontiers of Medicine

SN - 2095-0217

M1 - 1633624

ER -

ID: 143619947