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Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones. / Antonov, S. M.; Kalinina, N. I.; Kurchavyj, G. G.; Magazanik, L. G.; Shupliakov, O. V.; Vesselkin, N. P.

In: Neuroscience Letters, Vol. 109, No. 1-2, 05.02.1990, p. 82-87.

Research output: Contribution to journal › Article › peer-review

Harvard

Antonov, SM, Kalinina, NI, Kurchavyj, GG, Magazanik, LG, Shupliakov, OV & Vesselkin, NP 1990, 'Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones', Neuroscience Letters, vol. 109, no. 1-2, pp. 82-87. https://doi.org/10.1016/0304-3940(90)90541-G

APA

Antonov, S. M., Kalinina, N. I., Kurchavyj, G. G., Magazanik, L. G., Shupliakov, O. V., & Vesselkin, N. P. (1990). Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones. Neuroscience Letters, 109(1-2), 82-87. https://doi.org/10.1016/0304-3940(90)90541-G

Vancouver

Antonov SM, Kalinina NI, Kurchavyj GG, Magazanik LG, Shupliakov OV, Vesselkin NP. Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones. Neuroscience Letters. 1990 Feb 5;109(1-2):82-87. https://doi.org/10.1016/0304-3940(90)90541-G

Author

Antonov, S. M. ; Kalinina, N. I. ; Kurchavyj, G. G. ; Magazanik, L. G. ; Shupliakov, O. V. ; Vesselkin, N. P. / Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones. In: Neuroscience Letters. 1990 ; Vol. 109, No. 1-2. pp. 82-87.

BibTeX

@article{189e601805fd4a519cb1d3644f7e9e27,
title = "Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones",
abstract = "Synaptic responses induced in motoneurones by stimulation of dorsal root (DR) and reticular formation (RF) were recorded intracellularly in the isolated frog spinal cord. Argiopine (spider neurotoxin, a selective blocker of glutamate receptors of the non-N-methyl-d-aspartate (non-NMDA) type) in concentrations from 3 × 10-7 to 1 × 10-5 M effectively inhibited di- and polysynaptic components of excitatory postsynaptic potentials (EPSPs) induced by DR and RF stimulation. The monosynaptic component of the RF response was inhibited by argiopine, whereas the monosynaptic component of DR response was actually enhanced. All types of EPSPs studied were blocked by kynurenate (1ndash;2 × 10-3 M). d,l-2-Amino-5-phosphonovaleric acid (1 × 10-4 M slightly diminished the amplitude only of polysynaptic DR responses. A special type of argiopine-resistant, non-NMDA glutamate receptor is assumed to be involved in the generation of an EPSP by the monosynaptic DR input.",
keywords = "Argiopine, d,l-2-Amino-5-phosphonovaleric acid, Glutamate receptor, Kynurenate, Monosynaptic EPSP, Motoneuron, Polysynaptic EPSP, Spinal cord",
author = "Antonov, {S. M.} and Kalinina, {N. I.} and Kurchavyj, {G. G.} and Magazanik, {L. G.} and Shupliakov, {O. V.} and Vesselkin, {N. P.}",
year = "1990",
month = feb,
day = "5",
doi = "10.1016/0304-3940(90)90541-G",
language = "English",
volume = "109",
pages = "82--87",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier",
number = "1-2",

}

RIS

TY - JOUR

T1 - Identification of two types of excitatory monosynaptic inputs in frog spinal motoneurones

AU - Antonov, S. M.

AU - Kalinina, N. I.

AU - Kurchavyj, G. G.

AU - Magazanik, L. G.

AU - Shupliakov, O. V.

AU - Vesselkin, N. P.

PY - 1990/2/5

Y1 - 1990/2/5

N2 - Synaptic responses induced in motoneurones by stimulation of dorsal root (DR) and reticular formation (RF) were recorded intracellularly in the isolated frog spinal cord. Argiopine (spider neurotoxin, a selective blocker of glutamate receptors of the non-N-methyl-d-aspartate (non-NMDA) type) in concentrations from 3 × 10-7 to 1 × 10-5 M effectively inhibited di- and polysynaptic components of excitatory postsynaptic potentials (EPSPs) induced by DR and RF stimulation. The monosynaptic component of the RF response was inhibited by argiopine, whereas the monosynaptic component of DR response was actually enhanced. All types of EPSPs studied were blocked by kynurenate (1ndash;2 × 10-3 M). d,l-2-Amino-5-phosphonovaleric acid (1 × 10-4 M slightly diminished the amplitude only of polysynaptic DR responses. A special type of argiopine-resistant, non-NMDA glutamate receptor is assumed to be involved in the generation of an EPSP by the monosynaptic DR input.

AB - Synaptic responses induced in motoneurones by stimulation of dorsal root (DR) and reticular formation (RF) were recorded intracellularly in the isolated frog spinal cord. Argiopine (spider neurotoxin, a selective blocker of glutamate receptors of the non-N-methyl-d-aspartate (non-NMDA) type) in concentrations from 3 × 10-7 to 1 × 10-5 M effectively inhibited di- and polysynaptic components of excitatory postsynaptic potentials (EPSPs) induced by DR and RF stimulation. The monosynaptic component of the RF response was inhibited by argiopine, whereas the monosynaptic component of DR response was actually enhanced. All types of EPSPs studied were blocked by kynurenate (1ndash;2 × 10-3 M). d,l-2-Amino-5-phosphonovaleric acid (1 × 10-4 M slightly diminished the amplitude only of polysynaptic DR responses. A special type of argiopine-resistant, non-NMDA glutamate receptor is assumed to be involved in the generation of an EPSP by the monosynaptic DR input.

KW - Argiopine

KW - d,l-2-Amino-5-phosphonovaleric acid

KW - Glutamate receptor

KW - Kynurenate

KW - Monosynaptic EPSP

KW - Motoneuron

KW - Polysynaptic EPSP

KW - Spinal cord

UR - http://www.scopus.com/inward/record.url?scp=0025058515&partnerID=8YFLogxK

U2 - 10.1016/0304-3940(90)90541-G

DO - 10.1016/0304-3940(90)90541-G

M3 - Article

C2 - 2156195

AN - SCOPUS:0025058515

VL - 109

SP - 82

EP - 87

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 1-2

ER -

ID: 40839786