Giperpoliarizatsiia kozhi liagushki pri deǐstvii furosemida

Translated title of the contribution: Hyperpolarization of frog skin exposed to furosemide

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

When applied only to the outer surface of the isolated frog skin furosemide caused a prompt, dose-related (0.1--1.0 mg/ml) and fully reversible increase in potential difference; it did not change the short-circuit current, however. Potential differences were not altered by furosemide in the Ringer-sulphate solution. Furosemide-induced increase of potential differences could be reversed by nystatine which increased the ionic permeability. These results suggest that furosemide could decrease the passive entrance of chlorides through the barrier of the apical cell membrane of the frog skin.

Translated title of the contributionHyperpolarization of frog skin exposed to furosemide
Original languageRussian
Pages (from-to)69-71
Number of pages3
JournalByulleten Eksperimentalnoi Biologii i Meditsiny
Volume79
Issue number6
StatePublished - 1 Jun 1975

Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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