In this work we designed, synthesized and characterized luminescent metal nanoclusters (NCs) on human serum albumin (HSA) and immunoglobulins (Ig). We demonstrate that the approach developed allows one to determine the relative content of albumins and immunoglobulins in biologically relevant protein mixtures based on the luminescent properties of the NCs. Fast and inexpensive approach which allows to determine concentrations of immunoglobulins (Ig) and serum albumin (HSA) in blood serum might be useful in clinical diagnostics.
|Journal||Journal of Physics: Conference Series|
|State||Published - 2020|
|Event||7th International School and Conference "Saint-Petersburg OPEN 2020" on Optoelectronics, Photonics, Engineering and Nanostructures - Санкт-Петербург, Russian Federation|
Duration: 26 Apr 2020 → 30 Apr 2020