Abstract

The serious problem of current day is the processes involved in wound healing and chronic wounds treatment. The best investing strategyin treatment of chronic wounds is the bactericidal effect of non-thermal atmospheric pressure plasma. The paper presents experimental results of full-skin wounds healing in mice on the background of immune suppression when treating the wound surface with non-thermal plasma. A comprehensive analysis of changes in the wound surface area, bacterial contamination and IL-10 level under the influence of non-thermal plasma revealed signs of accelerated re-epithelialization and stimulation of epithelial cell proliferation, indicating activation of the healing process.
Original languageEnglish
Article number156
Pages (from-to)1132-1140
Number of pages9
JournalResearch Journal of Pharmaceutical, Biological and Chemical Sciences
Volume10
Issue number2
Publication statusPublished - Mar 2019

Cite this

@article{85164b4b99d547148e3cabb1b5f02c56,
title = "Dynamics Of IL-10 Level In Mice Skin Wounds Under The Bactericidal Influence Of Non-Thermal Plasma.",
abstract = "The serious problem of current day is the processes involved in wound healing and chronic wounds treatment. The best investing strategyin treatment of chronic wounds is the bactericidal effect of non-thermal atmospheric pressure plasma. The paper presents experimental results of full-skin wounds healing in mice on the background of immune suppression when treating the wound surface with non-thermal plasma. A comprehensive analysis of changes in the wound surface area, bacterial contamination and IL-10 level under the influence of non-thermal plasma revealed signs of accelerated re-epithelialization and stimulation of epithelial cell proliferation, indicating activation of the healing process.",
keywords = "cytokines, IL-10, skin wounds micro biota, wound healing, non-thermal atmospheric pressure plasma",
author = "Орлова, {Ольга Геннадьевна} and Парийская, {Елена Николаевна} and Захарова, {Лидия Борисовна} and Голованова, {Наталья Эриковна} and Астратенкова, {Ирина Викторовна} and Рыбальченко, {Оксана Владимировна}",
year = "2019",
month = "3",
language = "English",
volume = "10",
pages = "1132--1140",
journal = "Research Journal of Pharmaceutical, Biological and Chemical Sciences",
issn = "0975-8585",
publisher = "RJPBCS",
number = "2",

}

TY - JOUR

T1 - Dynamics Of IL-10 Level In Mice Skin Wounds Under The Bactericidal Influence Of Non-Thermal Plasma.

AU - Орлова, Ольга Геннадьевна

AU - Парийская, Елена Николаевна

AU - Захарова, Лидия Борисовна

AU - Голованова, Наталья Эриковна

AU - Астратенкова, Ирина Викторовна

AU - Рыбальченко, Оксана Владимировна

PY - 2019/3

Y1 - 2019/3

N2 - The serious problem of current day is the processes involved in wound healing and chronic wounds treatment. The best investing strategyin treatment of chronic wounds is the bactericidal effect of non-thermal atmospheric pressure plasma. The paper presents experimental results of full-skin wounds healing in mice on the background of immune suppression when treating the wound surface with non-thermal plasma. A comprehensive analysis of changes in the wound surface area, bacterial contamination and IL-10 level under the influence of non-thermal plasma revealed signs of accelerated re-epithelialization and stimulation of epithelial cell proliferation, indicating activation of the healing process.

AB - The serious problem of current day is the processes involved in wound healing and chronic wounds treatment. The best investing strategyin treatment of chronic wounds is the bactericidal effect of non-thermal atmospheric pressure plasma. The paper presents experimental results of full-skin wounds healing in mice on the background of immune suppression when treating the wound surface with non-thermal plasma. A comprehensive analysis of changes in the wound surface area, bacterial contamination and IL-10 level under the influence of non-thermal plasma revealed signs of accelerated re-epithelialization and stimulation of epithelial cell proliferation, indicating activation of the healing process.

KW - cytokines

KW - IL-10

KW - skin wounds micro biota

KW - wound healing

KW - non-thermal atmospheric pressure plasma

M3 - Article

VL - 10

SP - 1132

EP - 1140

JO - Research Journal of Pharmaceutical, Biological and Chemical Sciences

JF - Research Journal of Pharmaceutical, Biological and Chemical Sciences

SN - 0975-8585

IS - 2

M1 - 156

ER -