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The article reveals the features of Layer-by-Layer (LbL) direct synthesis of coatings consisting of core-shell CeO2@HxPO4·nH2O nanoparticles on the Ti surface. It is shown that the synthesis can be carried out at room temperature and atmospheric pressure using a colloidal aqueous solution of CeO2 and an aqueous solution of Na2HPO4 and simple automated setups. The study of the coatings by FESEM, TEM, HRTEM, SAED, XPS, EDX and FT-IR DR methods indicates that they consist of core-shell CeO2@HxPO4 nH2O nanoparticles having CeO2 core with a size of 2–3 nm and HPO42- and PO43- anions in the shell. Deposition of these coatings on the Ti surface significantly changes its wetting angle with water from 62° degrees to 38, 23, and 21° degrees for the samples prepared as a result of 5, 10, and 20 LbL cycles, respectively. In vitro testing of biocompatibility on human osteosarcoma U2OS cells by indirect and direct contact MTT assays demonstrated no significant cytotoxic effect of the obtained coating. Fluorescence microscopy showed that osteoblast-like cells attach and remain on the Ti surface with the CeO2@HxPO4·nH2O coating. © © 2025. Published by Elsevier B.V.
Original languageEnglish
JournalColloids and Surfaces A: Physicochemical and Engineering Aspects
Volume733
DOIs
StatePublished - 20 Mar 2026

    Research areas

  • Biocompatibility, Ce(IV) oxide, Core-shell, LbL, Osteoblast-like cells, Phosphate, Atmospheric pressure, Cerium oxide, Coatings, Cytotoxicity, Deposition, Fluorescence microscopy, Osteoblasts, Phosphorus compounds, Shells (structures), Sodium compounds, Sols, TiO2 nanoparticles, Titanium, Titanium oxides, Automated setup, CeO 2, Core shell, Direct synthesis, Layer by layer, Layer by layer deposition, Simple++, Tem/hrtem, Titania surfaces, nanoparticle, phosphate, titanium, aqueous solution, Article, atmospheric pressure, biocompatibility, cytotoxicity, fluorescence, fluorescence microscopy, human, human cell, in vitro study, layer by layer deposition, osteoblast, osteosarcoma, room temperature, synthesis

ID: 148346740