Different adhesion types and active sensitivity of platelet subpopulations

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Different adhesion types and active sensitivity of platelet subpopulations. / Zhao, B.; Filler, T. J.; Rickert, C. H.; Liu, J. F.; Skholl-Engberts, A. D.; Gurevich, V.

In: American Journal of Hematology, Vol. 52, No. 4, 08.1996, p. 322-324.

Research output: Contribution to journal › Article › peer-review

Author

Zhao, B. ; Filler, T. J. ; Rickert, C. H. ; Liu, J. F. ; Skholl-Engberts, A. D. ; Gurevich, V. / Different adhesion types and active sensitivity of platelet subpopulations. In: American Journal of Hematology. 1996 ; Vol. 52, No. 4. pp. 322-324.

BibTeX

@article{29a6a4ba5b6740ea9276b5b94160535a,

title = "Different adhesion types and active sensitivity of platelet subpopulations",

abstract = "Two different adhesion patterns of blood platelets with different sensitivity to adenosine were demonstrated by means of reflection contrast microscopy with consecutive image analysis and cell affinity chromatography. High-performance liquid chromatography revealed that thrombin-induced serotonin release of adenosine-sensitive platelets was lower than that of adenosine-resistant cells. Our results indicate platelet heterogeneity and suggest that the platelets with lower adenosine sensitivity may be actively involved in the early interaction between platelets and injured endothelium.",

keywords = "adenosine binding, blood platelets, heterogeneity, platelet adhesion, serotonin",

author = "B. Zhao and Filler, {T. J.} and Rickert, {C. H.} and Liu, {J. F.} and Skholl-Engberts, {A. D.} and V. Gurevich",

year = "1996",

month = aug,

doi = "10.1002/(SICI)1096-8652(199608)52:4<322::AID-AJH15>3.0.CO;2-F",

language = "English",

volume = "52",

pages = "322--324",

journal = "American Journal of Hematology",

issn = "0361-8609",

publisher = "Wiley-Blackwell",

number = "4",

}

RIS

TY - JOUR

T1 - Different adhesion types and active sensitivity of platelet subpopulations

AU - Zhao, B.

AU - Filler, T. J.

AU - Rickert, C. H.

AU - Liu, J. F.

AU - Skholl-Engberts, A. D.

AU - Gurevich, V.

PY - 1996/8

Y1 - 1996/8

N2 - Two different adhesion patterns of blood platelets with different sensitivity to adenosine were demonstrated by means of reflection contrast microscopy with consecutive image analysis and cell affinity chromatography. High-performance liquid chromatography revealed that thrombin-induced serotonin release of adenosine-sensitive platelets was lower than that of adenosine-resistant cells. Our results indicate platelet heterogeneity and suggest that the platelets with lower adenosine sensitivity may be actively involved in the early interaction between platelets and injured endothelium.

AB - Two different adhesion patterns of blood platelets with different sensitivity to adenosine were demonstrated by means of reflection contrast microscopy with consecutive image analysis and cell affinity chromatography. High-performance liquid chromatography revealed that thrombin-induced serotonin release of adenosine-sensitive platelets was lower than that of adenosine-resistant cells. Our results indicate platelet heterogeneity and suggest that the platelets with lower adenosine sensitivity may be actively involved in the early interaction between platelets and injured endothelium.

KW - adenosine binding

KW - blood platelets

KW - heterogeneity

KW - platelet adhesion

KW - serotonin

UR - http://www.scopus.com/inward/record.url?scp=0029767658&partnerID=8YFLogxK

U2 - 10.1002/(SICI)1096-8652(199608)52:4<322::AID-AJH15>3.0.CO;2-F

DO - 10.1002/(SICI)1096-8652(199608)52:4<322::AID-AJH15>3.0.CO;2-F

M3 - Article

C2 - 8701954

VL - 52

SP - 322

EP - 324

JO - American Journal of Hematology

JF - American Journal of Hematology

SN - 0361-8609

IS - 4

ER -

ID: 38777438