Convenient modular construction of medicinally important 5-acylamino-4,5-dihydroisoxazoles featuring four elements of diversity

Alexandra Kulyashova, Mikhail Krasavin

Research output

5 Citations (Scopus)

Abstract

An efficient modular approach toward medicinally important 5-acylamino-4,5-isoxazolines via the 1,3-dipolar cycloaddition reaction of nitrile oxides and MCR-derived enamide building blocks is described. This approach results in isoxazolines containing four elements of diversity utilizing two practically simple synthetic operations.
Original languageEnglish
Pages (from-to)4395-4397
JournalTetrahedron Letters
Volume57
Issue number39
Publication statusPublished - 2016

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