Concise synthesis of 2-N-hydroxy-3,4-dihydroisoquinol-2-one: A bacterial siderophore and human 5-lipooxygenase inhibitor

Research output

4 Citations (Scopus)

Abstract

A short synthesis of 2-N-hydroxy-3,4-dihydroisoquinol-2-one has been devised, which is based on the Castagnoli-Cushman reaction and 3 times more high-yielding compared to an earlier reported sequence.

Original languageEnglish
Pages (from-to)1511-1512
Number of pages2
JournalTetrahedron Letters
Volume59
Issue number15
DOIs
Publication statusPublished - 11 Apr 2018

Scopus subject areas

  • Drug Discovery
  • Biochemistry
  • Organic Chemistry

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