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Cellularity of lymphoid organs and immune response of mice at later times following irradiation. / Samoilovich, M. P.; Klimovich, V. B.

In: Radiobiologiya, Vol. 22, No. 3, 1982, p. 359-364.

Research output: Contribution to journal › Article › peer-review

Harvard

Samoilovich, MP & Klimovich, VB 1982, 'Cellularity of lymphoid organs and immune response of mice at later times following irradiation', Radiobiologiya, vol. 22, no. 3, pp. 359-364.

APA

Samoilovich, M. P., & Klimovich, V. B. (1982). Cellularity of lymphoid organs and immune response of mice at later times following irradiation. Radiobiologiya, 22(3), 359-364.

Vancouver

Samoilovich MP, Klimovich VB. Cellularity of lymphoid organs and immune response of mice at later times following irradiation. Radiobiologiya. 1982;22(3):359-364.

Author

Samoilovich, M. P. ; Klimovich, V. B. / Cellularity of lymphoid organs and immune response of mice at later times following irradiation. In: Radiobiologiya. 1982 ; Vol. 22, No. 3. pp. 359-364.

BibTeX

@article{4cc0cc4e046f43d891676c09d96f2774,
title = "Cellularity of lymphoid organs and immune response of mice at later times following irradiation",
abstract = "The immunological status of CBA mice surviving 2-11 months after X-irradiation in a dose 5 Gy was investigated. The immune response against sheep erythrocytes in the spleen recovered in 5 months after irradiation, but in the lymph nodes it was not normalized in 8 months. The hypoplasia of thymus and lymph nodes was observed in all irradiated mice whereas the cellularity of the spleen and bone marrow and the T/B-lymphocyte ratio in all lymphoid organs did not differ from normal. The dependence of the immune response upon the antigen dose was less pronounced in the irradiated animals than in the controls. The dynamics of the response in compared groups was similar. The results obtained indicate that there are distinctions between late radiation-induced immunodepression and immunologic insufficiency during acute radiation sickness and that there is organ specificity in the postirradiation recovery of different parts of the lymphoid system.",
author = "Samoilovich, {M. P.} and Klimovich, {V. B.}",
year = "1982",
language = "English",
volume = "22",
pages = "359--364",
journal = "РАДИАЦИОННАЯ БИОЛОГИЯ. РАДИОЭКОЛОГИЯ",
issn = "0869-8031",
publisher = "Издательство {"}Наука{"}",
number = "3",

}

RIS

TY - JOUR

T1 - Cellularity of lymphoid organs and immune response of mice at later times following irradiation

AU - Samoilovich, M. P.

AU - Klimovich, V. B.

PY - 1982

Y1 - 1982

N2 - The immunological status of CBA mice surviving 2-11 months after X-irradiation in a dose 5 Gy was investigated. The immune response against sheep erythrocytes in the spleen recovered in 5 months after irradiation, but in the lymph nodes it was not normalized in 8 months. The hypoplasia of thymus and lymph nodes was observed in all irradiated mice whereas the cellularity of the spleen and bone marrow and the T/B-lymphocyte ratio in all lymphoid organs did not differ from normal. The dependence of the immune response upon the antigen dose was less pronounced in the irradiated animals than in the controls. The dynamics of the response in compared groups was similar. The results obtained indicate that there are distinctions between late radiation-induced immunodepression and immunologic insufficiency during acute radiation sickness and that there is organ specificity in the postirradiation recovery of different parts of the lymphoid system.

AB - The immunological status of CBA mice surviving 2-11 months after X-irradiation in a dose 5 Gy was investigated. The immune response against sheep erythrocytes in the spleen recovered in 5 months after irradiation, but in the lymph nodes it was not normalized in 8 months. The hypoplasia of thymus and lymph nodes was observed in all irradiated mice whereas the cellularity of the spleen and bone marrow and the T/B-lymphocyte ratio in all lymphoid organs did not differ from normal. The dependence of the immune response upon the antigen dose was less pronounced in the irradiated animals than in the controls. The dynamics of the response in compared groups was similar. The results obtained indicate that there are distinctions between late radiation-induced immunodepression and immunologic insufficiency during acute radiation sickness and that there is organ specificity in the postirradiation recovery of different parts of the lymphoid system.

UR - http://www.scopus.com/inward/record.url?scp=0020134912&partnerID=8YFLogxK

M3 - Article

C2 - 6981825

AN - SCOPUS:0020134912

VL - 22

SP - 359

EP - 364

JO - РАДИАЦИОННАЯ БИОЛОГИЯ. РАДИОЭКОЛОГИЯ

JF - РАДИАЦИОННАЯ БИОЛОГИЯ. РАДИОЭКОЛОГИЯ

SN - 0869-8031

IS - 3

ER -

ID: 89782208