Bacterial Effect on the Crystallization of Mineral Phases in a Solution Simulating Human Urine

Ольга Викторовна Франк-Каменецкая, Алина Ростамовна Изатулина, Антон Михайлович Николаев, Мария Анатольевна Кузьмина, Владимир Васильевич Малышев

Research output

Abstract

The effect of bacteria that present in the human urine (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus) was studied under the conditions of biomimetic synthesis. It was shown that the addition of bacteria significantly affects both the phase composition of the synthesized material and the position of crystallization boundaries of the resulting phosphate phases, which can shift toward more acidic (struvite, apatite) or toward more alkaline (brushite) conditions. Under conditions of oxalate mineralization, bacteria accelerate the nucleation of calcium oxalates by almost two times and also increase the amount of oxalate precipitates along with phosphates and stabilize the calcium oxalate dihydrate (weddellite). The multidirectional changes in the pH values of the solutions, which are the result of the interaction of all system components and the crystallization process, were analyzed. The obtained results are the scientific basis for understanding the mechanisms of bacterial involvement in stone formation within the human body and the creation of biotechnological methods that inhibit this process.

Original languageEnglish
Article number259
JournalCrystals
Volume 9,
Issue number5
DOIs
Publication statusPublished - May 2019

Fingerprint

urine
oxalates
Crystallization
Minerals
Bacteria
Calcium Oxalate
Oxalates
minerals
crystallization
bacteria
Calcium
Phosphates
calcium
Apatites
phosphates
Apatite
Klebsiella
Biomimetics
pneumonia
Phase composition

Scopus subject areas

  • Chemical Engineering(all)
  • Materials Science(all)
  • Condensed Matter Physics
  • Inorganic Chemistry

Cite this

Франк-Каменецкая, Ольга Викторовна ; Изатулина, Алина Ростамовна ; Николаев, Антон Михайлович ; Кузьмина, Мария Анатольевна ; Малышев, Владимир Васильевич. / Bacterial Effect on the Crystallization of Mineral Phases in a Solution Simulating Human Urine. In: Crystals. 2019 ; Vol. 9, No. 5.
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abstract = "The effect of bacteria that present in the human urine (Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, and Staphylococcus aureus) was studied under the conditions of biomimetic synthesis. It was shown that the addition of bacteria significantly affects both the phase composition of the synthesized material and the position of crystallization boundaries of the resulting phosphate phases, which can shift toward more acidic (struvite, apatite) or toward more alkaline (brushite) conditions. Under conditions of oxalate mineralization, bacteria accelerate the nucleation of calcium oxalates by almost two times and also increase the amount of oxalate precipitates along with phosphates and stabilize the calcium oxalate dihydrate (weddellite). The multidirectional changes in the pH values of the solutions, which are the result of the interaction of all system components and the crystallization process, were analyzed. The obtained results are the scientific basis for understanding the mechanisms of bacterial involvement in stone formation within the human body and the creation of biotechnological methods that inhibit this process.",
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Bacterial Effect on the Crystallization of Mineral Phases in a Solution Simulating Human Urine. / Франк-Каменецкая, Ольга Викторовна; Изатулина, Алина Ростамовна; Николаев, Антон Михайлович; Кузьмина, Мария Анатольевна; Малышев, Владимир Васильевич.

In: Crystals, Vol. 9, No. 5, 259, 05.2019.

Research output

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AU - Изатулина, Алина Ростамовна

AU - Николаев, Антон Михайлович

AU - Кузьмина, Мария Анатольевна

AU - Малышев, Владимир Васильевич

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