Application of lanthanum stearate monolayers as a metal-affinity sorbent for the selective sorption of soman adducts to human serum albumin

V. N. Babakov, E. V. Shreiner, O. A. Keltsieva, Y. A. Dubrovskii, V. V. Shilovskikh, I. M. Zorin, N. G. Sukhodolov, I. G. Zenkevich, E. P. Podolskaya, A. A. Selyutin

Research output: Contribution to journalArticleResearchpeer-review

Abstract

A new metal-affinity sorbent based on lanthanum stearate monolayers has been developed and characterized. The prospect of its application to specific extraction of organophosphorous compound (OP) adducts of blood proteins was demonstrated. For this, the patterns of soman adducts of human serum albumin (HSA) were comprehensively characterized by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS).

LanguageEnglish
Pages728-731
Number of pages4
JournalTalanta
Volume195
DOIs
StatePublished - 1 Apr 2019

Keywords

  • Langmuir-Blodgett films
  • Lanthanum stearate
  • Organophosphorous compounds (OPs)
  • Serum albumin adducts

Scopus subject areas

  • Analytical Chemistry
  • Chemistry(all)
  • Biochemistry
  • Spectroscopy

Cite this

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title = "Application of lanthanum stearate monolayers as a metal-affinity sorbent for the selective sorption of soman adducts to human serum albumin",
abstract = "A new metal-affinity sorbent based on lanthanum stearate monolayers has been developed and characterized. The prospect of its application to specific extraction of organophosphorous compound (OP) adducts of blood proteins was demonstrated. For this, the patterns of soman adducts of human serum albumin (HSA) were comprehensively characterized by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS).",
keywords = "Langmuir-Blodgett films, Lanthanum stearate, Organophosphorous compounds (OPs), Serum albumin adducts",
author = "Babakov, {V. N.} and Shreiner, {E. V.} and Keltsieva, {O. A.} and Dubrovskii, {Y. A.} and Shilovskikh, {V. V.} and Zorin, {I. M.} and Sukhodolov, {N. G.} and Zenkevich, {I. G.} and Podolskaya, {E. P.} and Selyutin, {A. A.}",
year = "2019",
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doi = "10.1016/j.talanta.2018.11.103",
language = "English",
volume = "195",
pages = "728--731",
journal = "Talanta",
issn = "0039-9140",
publisher = "Elsevier",

}

Application of lanthanum stearate monolayers as a metal-affinity sorbent for the selective sorption of soman adducts to human serum albumin. / Babakov, V. N.; Shreiner, E. V.; Keltsieva, O. A.; Dubrovskii, Y. A.; Shilovskikh, V. V.; Zorin, I. M.; Sukhodolov, N. G.; Zenkevich, I. G.; Podolskaya, E. P.; Selyutin, A. A.

In: Talanta, Vol. 195, 01.04.2019, p. 728-731.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Application of lanthanum stearate monolayers as a metal-affinity sorbent for the selective sorption of soman adducts to human serum albumin

AU - Babakov, V. N.

AU - Shreiner, E. V.

AU - Keltsieva, O. A.

AU - Dubrovskii, Y. A.

AU - Shilovskikh, V. V.

AU - Zorin, I. M.

AU - Sukhodolov, N. G.

AU - Zenkevich, I. G.

AU - Podolskaya, E. P.

AU - Selyutin, A. A.

PY - 2019/4/1

Y1 - 2019/4/1

N2 - A new metal-affinity sorbent based on lanthanum stearate monolayers has been developed and characterized. The prospect of its application to specific extraction of organophosphorous compound (OP) adducts of blood proteins was demonstrated. For this, the patterns of soman adducts of human serum albumin (HSA) were comprehensively characterized by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS).

AB - A new metal-affinity sorbent based on lanthanum stearate monolayers has been developed and characterized. The prospect of its application to specific extraction of organophosphorous compound (OP) adducts of blood proteins was demonstrated. For this, the patterns of soman adducts of human serum albumin (HSA) were comprehensively characterized by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS).

KW - Langmuir-Blodgett films

KW - Lanthanum stearate

KW - Organophosphorous compounds (OPs)

KW - Serum albumin adducts

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DO - 10.1016/j.talanta.2018.11.103

M3 - Article

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SP - 728

EP - 731

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T2 - Talanta

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