Application of lanthanum stearate monolayers as a metal-affinity sorbent for the selective sorption of soman adducts to human serum albumin

V. N. Babakov, E. V. Shreiner, O. A. Keltsieva, Y. A. Dubrovskii, V. V. Shilovskikh, I. M. Zorin, N. G. Sukhodolov, I. G. Zenkevich, E. P. Podolskaya, A. A. Selyutin

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

A new metal-affinity sorbent based on lanthanum stearate monolayers has been developed and characterized. The prospect of its application to specific extraction of organophosphorous compound (OP) adducts of blood proteins was demonstrated. For this, the patterns of soman adducts of human serum albumin (HSA) were comprehensively characterized by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF-MS).

Original languageEnglish
Pages (from-to)728-731
Number of pages4
JournalTalanta
Volume195
DOIs
StatePublished - 1 Apr 2019

Scopus subject areas

  • Analytical Chemistry
  • Chemistry(all)
  • Biochemistry
  • Spectroscopy

Keywords

  • Langmuir-Blodgett films
  • Lanthanum stearate
  • Organophosphorous compounds (OPs)
  • Serum albumin adducts

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