Antimutagenic Systems Based on Chitosan Conjugates with Plant Antioxidants

V.A. Alexandrova, N.S. Domnina, G.P. Snigireva

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

It was shown using various methods that the radical scavenging and radical scavenging activities of chitosan conjugates with phenolic antioxidants of plant origin significantly exceed the corresponding values of their low molecular weight analogs (gallic and syringic acids, quercetin and dihydroquercetin). Cytogenetic analysis of human peripheral blood lymphocytes demonstrated that the conjugates showed pronounced antimutagenic efficiency when the cells were γ-irradiated in vitro at a dose of 2 Gy.
Original languageEnglish
Pages (from-to)491-495
Number of pages5
JournalApplied Biochemistry and Microbiology
Volume52
Issue number5
DOIs
StatePublished - 2016

Keywords

  • antimutagenic efficiency
  • antioxidative activity
  • chitosan
  • chitosan conjugates
  • phenolic antioxidants
  • quaternized chitosan

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