Antimutagenic effect of chemosignals from isolated female house mouse on male germ cells (Mus musculus L)

E.V. Daev, Y.A. Bezruchko, A.V. Dukelskaya

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The influence of chemosignals from isolated mature females of the CBA line on level of spontaneous and radiation-induced meiotic disturbances in spermatocytes I of males of the same line was studied. Using an ana-telophase method, 24-hour exposure of males to soiled bedding containing isolated females chemosignals was shown to lead to a significantly lower frequency of chromosomal aberrations and other meiotic disturbances in spermatocytes I as compared to males kept on clean bedding. The same effect of female chemosignals was found in the reproductive cells of irradiated males (4 Gr). The mechanisms and importance of the revealed antimutagenic effect of mouse female chemosignals on the male reproductive cells in the reproduction process are discussed.

Original languageEnglish
Pages (from-to)621-625
Number of pages6
JournalRussian Journal of Genetics
Volume50
Issue number6
DOIs
StatePublished - 2014

Scopus subject areas

  • Medicine(all)

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