An elastic gel-channel system mimicking non-linear flows in meningeal lymphatic microvessels

Alexander V. Sychev, Vasily E. Melnichenko, Anastasia I. Lavrova, Eugene B. Postnikov

Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

Abstract

One of the modern challenges in the field of the brain’s physiology is the study of the functioning of the recently discovered meningeal lymphatic vessels. Due to their microscopic size and complicated accessibility in vivo, the equivalent microfluidics devices, which mimic the elasticity of microvessels and their environment as well as lymph’s flow, should play an important role for testing appropriate mathematical models of the transport processes in such a tissue. We present both the experimental system and the respective model of non-linear elasto-diffusivity, which captures the key features of the flow carrying a marker spreading inside a meningeal lymphatic microvessel.

Original languageEnglish
Title of host publicationLifeTech 2021 - 2021 IEEE 3rd Global Conference on Life Sciences and Technologies
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages432-433
Number of pages2
ISBN (Electronic)9781665418751
DOIs
StatePublished - 9 Mar 2021
Event3rd IEEE Global Conference on Life Sciences and Technologies, LifeTech 2021 - Nara, Japan
Duration: 9 Mar 202111 Mar 2021

Publication series

NameLifeTech 2021 - 2021 IEEE 3rd Global Conference on Life Sciences and Technologies

Conference

Conference3rd IEEE Global Conference on Life Sciences and Technologies, LifeTech 2021
Country/TerritoryJapan
CityNara
Period9/03/2111/03/21

Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health(social science)
  • Biochemistry
  • Artificial Intelligence
  • Computer Science Applications

Keywords

  • Barenblatt-Pattle solution
  • Meningeal lymphatics
  • Microfluidics
  • Tissue engineering

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