Research output: Contribution to journal › Article › peer-review
Aerobic oxidation of imidazolines to 2-arylimidazoles using CuSO4∙H2O as a catalyst. / Юсубов, М.С.; Мячина, К. А.; Семенов, Артем Валерьевич; Шуриков, М.К.; Дарьин, Дмитрий Викторович; Байков, Сергей Валентинович; Солдатова, Наталья; Постников, П.С.
In: Synthesis, 22.09.2025.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Aerobic oxidation of imidazolines to 2-arylimidazoles using CuSO4∙H2O as a catalyst
AU - Юсубов, М.С.
AU - Мячина, К. А.
AU - Семенов, Артем Валерьевич
AU - Шуриков, М.К.
AU - Дарьин, Дмитрий Викторович
AU - Байков, Сергей Валентинович
AU - Солдатова, Наталья
AU - Постников, П.С.
PY - 2025/9/22
Y1 - 2025/9/22
N2 - Imidazoles are considered the merit heterocyclic moiety in medicinal chemistry and drug design. Here, we report the convenient method for the aerobic oxidation of imidazolines under mild conditions using cheap and available CuSO4 ·5H2O as the catalyst. The proposed method allows to prepare 2-arylimidazoles bearing electron-donating and withdrawing groups in good and quantitative yields. The developed procedure is applicable for the preparation of labile and oxidation-intolerant heterocyclic moieties.
AB - Imidazoles are considered the merit heterocyclic moiety in medicinal chemistry and drug design. Here, we report the convenient method for the aerobic oxidation of imidazolines under mild conditions using cheap and available CuSO4 ·5H2O as the catalyst. The proposed method allows to prepare 2-arylimidazoles bearing electron-donating and withdrawing groups in good and quantitative yields. The developed procedure is applicable for the preparation of labile and oxidation-intolerant heterocyclic moieties.
UR - http://www.thieme-connect.de/DOI/DOI?10.1055/a-2705-5409
UR - https://www.mendeley.com/catalogue/4207c457-0e75-329e-b68a-9dfc55188ee1/
U2 - 10.1055/a-2705-5409
DO - 10.1055/a-2705-5409
M3 - Article
JO - Synthesis
JF - Synthesis
SN - 0039-7881
ER -
ID: 141951856