Acetylene in Organic Synthesis: Recent Progress and New Uses

Владимир Владимирович Воронин, Мария Сергеевна Ледовская, Александр Сергеевич Богаченков, Константин Сергеевич Родыгин, Валентин Павлович Анаников

Research output: Contribution to journalReview articlepeer-review

52 Scopus citations

Abstract

Recent progress in the leading synthetic applications of acetylene is discussed from the prospect of rapid development and novel opportunities. A diversity of reactions involving the acetylene molecule to carry out vinylation processes, cross-coupling reactions, synthesis of substituted alkynes, preparation of heterocycles and the construction of a number of functionalized molecules with different levels of molecular complexity were recently studied. Of particular importance is the utilization of acetylene in the synthesis of pharmaceutical substances and drugs. The increasing interest in acetylene and its involvement in organic transformations highlights a fascinating renaissance of this simplest alkyne molecule.

Original languageEnglish
Article number2442
JournalMolecules
Volume23
Issue number10
DOIs
StatePublished - 24 Sep 2018

Scopus subject areas

  • Analytical Chemistry
  • Chemistry (miscellaneous)
  • Molecular Medicine
  • Pharmaceutical Science
  • Drug Discovery
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Keywords

  • Acetylene
  • Addition reactions
  • Biologically active molecule
  • Cross-coupling
  • Drugs
  • Monomers
  • Pharmaceutical substances
  • Polymers
  • Vinylation

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