Abstract
A novel gold(I) complex based on an aminotriazole N-heterocylic carbene ligand represents a promising scaffold for the design of anticancer bioorganometallics. The complex triggered cytotoxic effects in HT-29 and MDA-MB-231 cancer cells, inhibited the activity of the enzyme thioredoxin reductase and showed an effective and fast cellular accumulation.
Original language | English |
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Pages (from-to) | 1186-1189 |
Journal | MedChemComm |
Volume | 6 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2015 |