A building block approach to monofluorinated organic compounds

Research output

11 Citations (Scopus)

Abstract

Building blocks for the synthesis of monofluorinated organic compounds are reviewed. The synthetic potential of polyhalomethanes, sulfur- and phosphorus-containing building blocks, difluoroethene, polyhaloethanes, fluoroacetic acid derivatives, and other compounds are described. Pericyclic reactions involving fluorinated compounds and application of the methodology of building blocks to the synthesis of monofluorinated pharmaceuticals and analogs of natural compounds are considered. The review with 317 references covers mainly the literature from 1996 through 2007.

Original languageEnglish
Pages (from-to)1553-1611
Number of pages59
JournalCollection of Czechoslovak Chemical Communications
Volume73
Issue number12
DOIs
Publication statusPublished - 1 Dec 2008

Fingerprint

Organic compounds
Sulfur
Phosphorus
Derivatives
Pharmaceutical Preparations
fluoroacetic acid

Scopus subject areas

  • Chemistry(all)

Cite this

@article{7adbb8e1ad1a4070afbe998cfd7a3e69,
title = "A building block approach to monofluorinated organic compounds",
abstract = "Building blocks for the synthesis of monofluorinated organic compounds are reviewed. The synthetic potential of polyhalomethanes, sulfur- and phosphorus-containing building blocks, difluoroethene, polyhaloethanes, fluoroacetic acid derivatives, and other compounds are described. Pericyclic reactions involving fluorinated compounds and application of the methodology of building blocks to the synthesis of monofluorinated pharmaceuticals and analogs of natural compounds are considered. The review with 317 references covers mainly the literature from 1996 through 2007.",
keywords = "Fluorinated building blocks, Fluorinated organic compounds, Synthesis design",
author = "Konev, {Alexander S.} and Khlebnikov, {Alexander F.}",
year = "2008",
month = "12",
day = "1",
doi = "10.1135/cccc20081553",
language = "English",
volume = "73",
pages = "1553--1611",
journal = "ChemPlusChem",
issn = "2192-6506",
publisher = "Wiley-Blackwell",
number = "12",

}

TY - JOUR

T1 - A building block approach to monofluorinated organic compounds

AU - Konev, Alexander S.

AU - Khlebnikov, Alexander F.

PY - 2008/12/1

Y1 - 2008/12/1

N2 - Building blocks for the synthesis of monofluorinated organic compounds are reviewed. The synthetic potential of polyhalomethanes, sulfur- and phosphorus-containing building blocks, difluoroethene, polyhaloethanes, fluoroacetic acid derivatives, and other compounds are described. Pericyclic reactions involving fluorinated compounds and application of the methodology of building blocks to the synthesis of monofluorinated pharmaceuticals and analogs of natural compounds are considered. The review with 317 references covers mainly the literature from 1996 through 2007.

AB - Building blocks for the synthesis of monofluorinated organic compounds are reviewed. The synthetic potential of polyhalomethanes, sulfur- and phosphorus-containing building blocks, difluoroethene, polyhaloethanes, fluoroacetic acid derivatives, and other compounds are described. Pericyclic reactions involving fluorinated compounds and application of the methodology of building blocks to the synthesis of monofluorinated pharmaceuticals and analogs of natural compounds are considered. The review with 317 references covers mainly the literature from 1996 through 2007.

KW - Fluorinated building blocks

KW - Fluorinated organic compounds

KW - Synthesis design

UR - http://www.scopus.com/inward/record.url?scp=59849116724&partnerID=8YFLogxK

U2 - 10.1135/cccc20081553

DO - 10.1135/cccc20081553

M3 - Review article

AN - SCOPUS:59849116724

VL - 73

SP - 1553

EP - 1611

JO - ChemPlusChem

JF - ChemPlusChem

SN - 2192-6506

IS - 12

ER -