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    Author

    Михаил Юрьевич Красавин
2016
2 Citations (Scopus)
2017

Short Approach to Pyrrolopyrazino-, Pyrrolodiazepino-Isoindoles and their Benzo Analogues via the IMDAF Reaction

Zubkov, F. I., Orlova, D. N., Zaytsev, V. P., Voronov, A. A., Nikitina, E. V., Khrustalev, V. N., Novikov, R. A., Krasavin, M. & Varlamov, A. V., 2017, In : Current Organic Synthesis. 14, 5, p. 733-746 14 p.

Research output

2019
Bearings (structural)
Cycloaddition Reaction
Cyanides
5-hydroxymethylfurfural
2017
10 Citations (Scopus)

New nitrofurans amenable by isocyanide multicomponent chemistry are active against multidrug-resistant and poly-resistant Mycobacterium tuberculosis

Krasavin, M., Parchinsky, V., Kantin, G., Manicheva, O., Dogonadze, M., Vinogradova, T., Karge, B. & Brönstrup, M., 1 Jan 2017, In : Bioorganic and Medicinal Chemistry. 25, 6, p. 1867-1874 8 p.

Research output

Nitrofurans
Cyanides
Mycobacterium tuberculosis
Lactams
Pathogens
2018
3 Citations (Scopus)

The First Example of Azole-Fused Cyclic Anhydride Reacting in the Castagnoli-Cushman Way

Moreau, E., Dar'In, D. & Krasavin, M., 23 Apr 2018, In : Synlett. 29, 7, p. 890-893 4 p., st-2017-b0833-l.

Research output

Pyrazines
Azoles
Anhydrides
pyrazole
benzimidazole
2019
Imidazoles
Indoles
Amides
Carbon
Atoms
2010
12 Citations (Scopus)
2016
7 Citations (Scopus)
2019
4 Citations (Scopus)

Synthesis of various arylated trifluoromethyl substituted indanes and indenes, and study of their biological activity

Iakovenko, R. O., Chicca, A., Nieri, D., Reynoso-Moreno, I., Gertsch, J., Krasavin, M. & Vasilyev, A. V., Feb 2019, In : Tetrahedron. 75, 5, p. 624-632

Research output

Indenes
Bearings (structural)
Monoacylglycerol Lipases
Endocannabinoids
Cyclization
Tetrazoles
Silver Nitrate
Cycloaddition
Nitrates
Silver
2017
7 Citations (Scopus)
Amidines
Bioactivity
Pharmaceutical Preparations
2-imidazoline
2015
11 Citations (Scopus)
Open Access
Oxazepines
Bromine
Condensation reactions
Phenols
Cyclization
2015
16 Citations (Scopus)

Phenoxymethyl 1,3-oxazoles and 1,2,4-oxadiazoles as potent and selective agonists of free fatty acid receptor 1 (GPR40)

Zahanich, I., Kondratov, I., Naumchyk, V., Kheylik, Y., Platonov, M., Zozulya, S. & Krasavin, M., 2015, In : Bioorganic and Medicinal Chemistry Letters. p. 3105-3111

Research output

12 Citations (Scopus)

Panel docking of small-molecule libraries — Prospects to improve efficiency of lead compound discovery

Sarnpitak, P., Mujumdar, P., Taylor, P., Cross, M., Coster, M. J., Gorse, A-D., Krasavin, M. & Hofmann, A., 2015, In : Biotechnology Advances.

Research output

2017
4 Citations (Scopus)
Hydroxamic Acids
Siderophores
Oximes
Iron
Iron Chelating Agents
2014
4 Citations (Scopus)
2018

Synthesis and medicinal applications of n-aryl-c-nitroazoles

Chuprun, S. S., Kantin, G. & Krasavin, M., 1 Jan 2018, In : Mini-Reviews in Medicinal Chemistry. 18, 20, p. 1733-1752 20 p.

Research output

Pharmaceutical Chemistry
Research
Pharmaceutical Preparations
Renaissance
2016
9 Citations (Scopus)
2016
2 Citations (Scopus)
Pyrazoles
Platinum
Phosphorescence
Ligands
Charge transfer
2019

Spirocyclic motifs in natural products

Chupakhin, E., Babich, O., Prosekov, A., Asyakina, L. & Krasavin, M., 17 Nov 2019, In : Molecules. 24, 22, 37 p., 4165.

Research output

Open Access
Biological Products
products
Drug Discovery
voids
emerging
2 Citations (Scopus)

New antimycobacterial leads from multicomponent hydrazino-ugi reaction

Lakontseva, E., Karapetian, R. & Krasavin, M., 1 Mar 2016, In : Medicinal Chemistry. 12, 2, p. 191-199 9 p.

Research output

hydrazine
Tuberculosis
Diamide
Pyrazinamide
HEK293 Cells
2011

Practical Method for Parallel Synthesis of Diversely Substituted 1- henylpiperazines

Konstantinov, I., Bukhryakov, K., Gezentsvey, Y. & Krasavin, M., 2011, In : Letters in Organic Chemistry. 8, 9, p. 628-630

Research output

1 Citation (Scopus)
Sodium Azide
Microwave irradiation
Amines
Microwaves
chloroacetamide
10 Citations (Scopus)

Discovery and Preclinical Characterization of 3-((4-(4-Chlorophenyl)-7-fluoroquinoline-3-yl)sulfonyl)benzonitrile, a Novel Non-acetylenic Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator for Psychiatric Indications

Galambos, J., Bielik, A., Krasavin, M., Orgován, Z., Domány, G., Nógrádi, K., Wágner, G., Balogh, G. T., Béni, Z., Kóti, J., Szakács, Z., Bobok, A., Kolok, S., Mikó-Bakk, M. L., Vastag, M., Sághy, K., Laszy, J., Halász, A. S., Balázs, O., Gál, K. & 3 others, Greiner, I., Szombathelyi, Z. & Keserű, G. M., 23 Mar 2017, In : Journal of Medicinal Chemistry. 60, 6, p. 2470-2484 15 p.

Research output

Metabotropic Glutamate 5 Receptor
Psychiatry
Libraries
Anxiety
Depression
2018
6 Citations (Scopus)
Heterocyclic Compounds
heterocyclic compounds
Nitrogen compounds
Dicarboxylic Acids
Imines
2011
12 Citations (Scopus)
2016
6 Citations (Scopus)
2015
Cycloparaffins
Microwave irradiation
Microwaves
pyridine
tert-butylamine
2017
4 Citations (Scopus)

Continued SAR exploration of 1,2,4-thiadiazole-containing scaffolds in the design of free fatty acid receptor 1 (GPR40) agonists

Krasavin, M., Lukin, A., Bakholdina, A., Zhurilo, N., Onopchenko, O., Borysko, P., Zozulya, S., Moore, D. & Tikhonova, I. G., 1 Jan 2017, In : European Journal of Medicinal Chemistry. 140, p. 229-238 10 p.

Research output

Thiadiazoles
Nonesterified Fatty Acids
Scaffolds
Computer Simulation
Crystal structure
2016
4 Citations (Scopus)
2016
20 Citations (Scopus)
2019

BOB.1 controls memory B-cell fate in the germinal center reaction

Levels, M. J., Fehres, C. M., van Baarsen, L. G. M., van Uden, N. O. P., Germar, K., O'Toole, T. G., Blijdorp, I. C. J., Semmelink, J. F., Doorenspleet, M. E., Bakker, A. Q., Krasavin, M., Tomilin, A., Brouard, S., Spits, H., Baeten, D. L. P. & Yeremenko, N. G., Jul 2019, In : Journal of Autoimmunity. 101, p. 131-144

Research output

2018
5 Citations (Scopus)

Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase

Lukin, A., Kramer, J., Hartmann, M., Weizel, L., Hernandez-Olmos, V., Falahati, K., Burghardt, I., Kalinchenkova, N., Bagnyukova, D., Zhurilo, N., Rautio, J., Forsberg, M., Ihalainen, J., Auriola, S., Leppänen, J., Konstantinov, I., Pogoryelov, D., Proschak, E., Dar'in, D. & Krasavin, M., 1 Oct 2018, In : Bioorganic Chemistry. 80, p. 655-667 13 p.

Research output

Epoxide Hydrolases
Urea
Lead compounds
Pharmacokinetics
Enantiomers
2019
8 Citations (Scopus)
Azides
Scaffolds
Substrates
2017
10 Citations (Scopus)

Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds

Krasavin, M., Korsakov, M., Zvonaryova, Z., Semyonychev, E., Tuccinardi, T., Kalinin, S., Tanç, M. & Supuran, C. T., 1 Jan 2017, In : Bioorganic and Medicinal Chemistry. 25, 6, p. 1914-1925 12 p.

Research output

Carbonic Anhydrases
Sulfonamides
Scaffolds
Amines
Carbonic Anhydrase Inhibitors