Abstract
Copper-catalyzed azide–alkyne cycloaddition is a useful tool for the synthesis of both 1,2,3-triazoles and 5-iodo-1H-1,2,3-triazoles starting from either terminal alkynes or iodoalkynes. 5-Iodotriazoles have been recognized as very useful building blocks for the synthesis of diverse 1,4,5-trisubstituted 1,2,3-triazoles. Synthetic application of 5-iodo-1,2,3-triazoles through the creation of a new C–C, C–heteroatom, or C–D(T) bond along with the application areas of both iodotriazoles and products of their modification including radiolabeled compounds are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 1874–1896 |
| Number of pages | 23 |
| Journal | Synthesis |
| Volume | 52 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - 14 Apr 2020 |
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Danilkina, N. A., Govdi, A. I., & Balova, I. A. (2020). 5-Iodo-1H-1,2,3-triazoles as Versatile Building Blocks. Synthesis, 52(13), 1874–1896. https://doi.org/10.1055/s-0039-1690858