2H-Azirines in medicinal chemistry

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Abstract

[Figure not available: see fulltext.] The review presents an analysis of studies published in the period 1971–2020 devoted to examination of the biological activity of natural and synthetic 2H-azirine derivatives, their use for bioconjugation, as well as search for some new synthetic methods of structural modification of azirines with the aim of improving their biological activity.

Original languageEnglish
Pages (from-to)512-521
Number of pages10
JournalChemistry of Heterocyclic Compounds
Volume57
Issue number5
DOIs
StatePublished - May 2021

Scopus subject areas

  • Organic Chemistry

Keywords

  • 2Н-azirines
  • bioconjugation
  • biological activity
  • cycloaddition
  • natural compounds

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