The article describes a series of clinical cases of hepatitis in measles in children aged 8, 16 and 17 years. All cases were registered in St. Petersburg during the outbreak of measles in 2023–2024. In all patients, hepatitis was jaundice-free with an increase in ALT and AST levels within the upper 10 age limits, with moderate cholestasis. None of the patients had severe liver damage with signs of liver failure. All patients also had gastrointestinal disorders. Even though liver damage is not a typical manifestation of measles infection, there are few descriptions of clinical cases and studies on this issue in the literature. The severity of hepatitis ranges from mild to extremely severe, requiring emergency liver transplantation. The evidence of the etiological role of the measles virus in the development of hepatitis is the detection of the virus in hepatocytes, which is given in several publications. Damage to the gastrointestinal tract is also not included in the classic measles symptom complex but is considered one of the most common complications. This article demonstrates the possibility of developing hepatitis in measles, while emphasizing the lack of clear clinical symptoms, which may be the reason for underestimating the prevalence of liver involvement in this disease and lead to a lack of patient examination.
Translated title of the contributionCases of Hepatitis in Measles in Children During the Outbreak in Russia in 2023–2024
Original languageRussian
Pages (from-to)133-140
Number of pages8
JournalКЛИНИЧЕСКАЯ ИНФЕКТОЛОГИЯ И ПАРАЗИТОЛОГИЯ
Volume15
Issue number1
DOIs
StatePublished - 10 Mar 2026

    Research areas

  • AST, causes of increased ALT, gastrointestinal tract damage in measles, hepatitis in measles, liver damage in measles, measles in children, unspecified hepatitis

ID: 156131414