The mineral and chemical composition of Priozersky suite cement sandstones accommodating a uranium deposit of Karku discordance type located on the north-eastern shore of Lake Ladoga is studied. The selection performed and the study of cement sandstones apart from detrital matrix allows to divide the geochemical signals of different by composition and genesis rock components excluding the strong signal of the detrimal component from consideration. Cement of the main varieties of Priozersky suite sandstones including ore and near-ore zones are studied. Based on the structural and textural, mineralogical and pétrographic characteristics and X-ray analysis of cement mineral composition primary mineral associations varying by the ratio of minerals of kaolinite group, hydromicas and carbonates are identified. That is confirmed by the study of cement (by ISP-MC) chemical composition with the use of the factor analysis and the study of spectra of rare earth element distribution.