Электронная спектроскопия диффузного отражения в исследовании сыворотки крови с множественной миеломой.

Subject of Research. The paper presents testing and evaluation of the spectral method potential capabilities in relation to the study of human blood serum in normal and in patients with multiple myeloma. The study of samples of native and lyophilized serum is carried out in comparison with the spectral characteristics of aqueous extracts of animal muscle sarcoplasm. Method. A non-destructive diffuse reflection electron spectroscopy method with a vertical beam path in the wavelength range of 200-700 nm in the absorption format was used. Main Results. In contrast to the native donor serum, a band of mucopolysaccharides (410-415 nm) of different intensity has been observed in the spectra of samples of animal tissue sarcoplasm extracts. This band appeared in the spectra of donor serum after lyophilization. That is why the presence of the band of mucopolysaccharides in the patients' serum spectra is associated with reduced moisture binding capacity of the protein-polysaccharide complex, which, in turn, is due to th