A review of the main causes of male infertility in the aspect of the relationship with the degree of sperm DNA fragmentation is presented. Information is provided on the main methods for assessing sperm DNA fragmentation and its effect on male fertility. The effect of oxidative stress on the integrity of sperm DNA structure, the reparative capabilities of antioxidant therapy, and the effect of varicocele on male fertility are described.
|Translated title of the contribution||FRAGMENTATION OF SPERM DNA: CLINICAL SIGNIFICANCE, REASONS, METHODS OF EVALUATION AND CORRECTION|
|State||Published - 2020|