Первый отечественный опыт стереотаксической лучевой терапии на область ложа удаленной предстательной железы.

Роман Владимирович Новиков, Юлия Сергеевна Мельник, Сергей Николаевич Новиков

Research output: Contribution to journalArticle

Abstract

Purpose. Assess the safety of postoperative radiation therapy on the area of the prostate bed (PB) using extreme dose hypofractionation (5 fractions of 6.6-7 Gr). Materials and methods. from April 2019 to March 2020 at the National Medical Center of Oncology named after N.N. Petrov of the Ministry of Health of the Russian Federation in the first 15 patients of the prostate cancer carried out stereotactic radiation therapy (SRT) on the PB. Depending on the clinical situation, adjuvant and salvage SRT were distinguished. Linear electron accelerators with 6 MeV energy are used for treatment. Three factional regimes were evaluated: 5 factions of 6.6 Gr, 5 factions of 6.8 Gr and 5 factions of 7 Gr. The clinical target volume is defined by RTOG (2010). Results. The median of follow-up was 7.6 (1.3-11.6) months. Of the 15 patients, adjuvant SRT performed three observed, and the remaining 12 patients - salvage SRT (4 - early, 8 - delayed). Acute radiation toxicity was estimated in 12 patients. Early impairment from t
Original languageRussian
Pages (from-to)133-142
JournalУРОЛОГИЧЕСКИЕ ВЕДОМОСТИ
Volume10
Issue number2
StatePublished - 2020
Externally publishedYes

Keywords

  • adjuvant
  • Biochemical progression
  • Local relapse
  • radical prostatectomy
  • salvage
  • Stereotactic radiation therapy
  • адъювантная
  • биохимический рецидив
  • местный рецидив
  • радикальная простатэктомия
  • спасительная
  • стереотаксическая лучевая терапия

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