Клинические и структурно-функциональные особенности пароксизмальных расстройств, обусловленных опухолями островковой и височной долей

Translated title of the contribution: Clinical, structural and functional features of paroxismal syndrome in insular and temporal lobe tumors

Р. Г. Хачатрян, В. А. Барт, Л. Н. Маслова, Т. Н. Фадеева, К. И. Себелев, М. М. Тастанбеков, Т. М. Алексеева, В. А. Хачатрян

Research output: Contribution to journalArticlepeer-review

Abstract

OBJECTIVE: To analyze the characteristics of paroxysmal syndrome in insular and temporal lobe tumors, to determine their relationship with the histological structure of tumor, to assess the effect of tumor growth nature on severity of disease. MATERIAL AND METHODS: A retrospective analysis enrolled 80 patients aged 11 - 80 years with insular and temporal lobe tumors and symptomatic epilepsy. All patients underwent surgery at the Polenov National Research Neurosurgery Center in Almazov National Medical Research Center for the period from 2012 to 2018. RESULTS: The main group consisted of 29 patients with tumors of temporal and insular lobes. Control group of 51 patients with temporal gliomas was formed for comparative analysis. It was found that involvement of insular lobe into paroxysmal syndrome is characterized by attacks with a motor component, somatosensory paroxysms, vegetative manifestations (respiratory attacks, salivation, nausea), speech disorders and taste hallucinations. Derealization, motor arrest and déjà vu/jamis vu paroxysms were more common in patients with temporal lobe lesion. Neoplastic lesion of the insular lobe shortens the period between manifestation of paroxysms and surgical treatment. Moreover, this type of disease is characterized by higher incidence of seizures compared to isolated temporal lobe tumors.

Translated title of the contributionClinical, structural and functional features of paroxismal syndrome in insular and temporal lobe tumors
Original languageRussian
Pages (from-to)36-45
Number of pages10
JournalЖУРНАЛ ВОПРОСЫ НЕЙРОХИРУРГИИ ИМ. Н.Н. БУРДЕНКО
Volume84
Issue number4
DOIs
StatePublished - 1 Jan 2020

Scopus subject areas

  • Clinical Neurology

Keywords

  • Epilepsy surgery
  • Insular epilepsy
  • Insular glioma
  • Temporal lobe epilepsy

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