Кинетическое моделирование работы митохондриально-ретикулярной сети

Translated title of the contribution: KINETIC MODELING OF MITOCHONDRIAL-RETICULAR NETWORK DYNAMICS

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Abstract

This study indicates a mitochondrial-reticular network, functionally integrated into the processes that provide energy to all systems of the organism as open, dynamic, self-regulatory organization involved in the energy homeostasis of the cell under the control of AMP-activated protein kinase as the main energy indicator. The mitochondrial-reticular network is regulated by at least three multidirectional energy vectors - mitochondrial fission and fusion, and mitochondrial apoptosis mechanisms. A kinetic mathematical model of mitochondrial-reticular network function is proposed. A search for effective strategies for the functioning of mitochondrial-reticular network is resolved into constrained optimization through the use of the Lagrange multiplier.
Translated title of the contributionKINETIC MODELING OF MITOCHONDRIAL-RETICULAR NETWORK DYNAMICS
Original languageRussian
Pages (from-to)285-293
Number of pages9
JournalБИОФИЗИКА
Volume66
Issue number2
DOIs
StatePublished - Feb 2021

Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)
  • Medicine(all)
  • General

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