Advances in Microfluidic Biosensors Based on Luminescent Bacteria

Xiao Wei JIN, Zhe Yu LI, Pian Pian XU, Xiao Yan ZHANG, Nan Qi REN, Vitaliy V. Kurilenko, Kai SUN

Research output: Contribution to journalReview articlepeer-review


Luminescent bacteria can emit visible light at 450–490 nm, and its luminous intensity decreases with the increase of the concentration of toxic substances in test solution. The method using luminescent bacteria is widely used in acute toxicity analysis of water quality because it is a simple, rapid and low-cost way. In recent years, biosensors based on luminescent bacteria have attracted more and more attention, and the reports of bioluminescence biosensors based on microfluidic systems are increasing day by day. Based on the characteristics and mechanism of luminescent bacteria, this paper introduces their applications in the environmental monitoring, and summarizes several new bioluminescence sensors.

Translated title of the contributionДостижения в области микрофлюидных биосенсоров на основе люминесцентных бактерий
Original languageEnglish
Pages (from-to)181-189
Number of pages9
JournalChinese Journal of Analytical Chemistry
Issue number2
StatePublished - 1 Feb 2019

Scopus subject areas

  • Analytical Chemistry
  • Environmental Science(all)


  • Acute toxicity
  • Biosensor
  • Environmental pollutant
  • Luminescent bacteria
  • Microfluidic
  • Review


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