Barrier properties in porcine Peyer’s patches

J. Radloff, S.S. Zakrzewski, E. L. Falchuk, A. G. Markov, S. Amasheh

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Abstract

Representing the most important part of the intestinal immune system, Peyer’s patches (PP) form an aggregation of lymphocytes, macrophages and dendritic cells located just underneath the basal layer of the intestinal epithelium. The follicle-associated epithelium (FAE) contains specific cells (microfold cells) for antigen uptake and transport through the epithelial layer to the underlying PP immune cells. Therefore interactions with the immune system are possible. Since a tight intestinal barrier is a prerequisite for this function, we questioned whether in porcine intestine there are functional and molecular differences of tight junctions in comparison to villous epithelium
Translated title of the contributionБарьерные свойства эпителия Пейеровых бляшек кишки свиньи
Original languageEnglish
Pages165
StatePublished - 16 Mar 2017
EventAnnual Meeting of the German Physiological Society - Greifswald, Germany
Duration: 16 Mar 201718 Mar 2017
Conference number: 96
http://www.dpg2017.de/

Conference

ConferenceAnnual Meeting of the German Physiological Society
CountryGermany
CityGreifswald
Period16/03/1718/03/17
Internet address

Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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