Антиагреганты в первичной профилактике сердечно-сосудистых заболеваний и профилактике атеротромбоза у больных со стабильной формой ишемической болезни сердца: аспекты эффективности и безопасности

Research outputpeer-review

Abstract

This review is devoted to the use of antiaggregants. We consider here pathogenesis of intraarterial thrombosis, mechanism of action of antiaggregants, and recommendations on the use of drugs of this class for primary prevention of cardiovascular diseases and prevention of atherothrombotic complications of stable ischemic heart disease. Information on mechanisms of development and causes of resistance to antiaggregants is also presented. Finally we discuss the problem of safety of therapy with antiaggregants, methods of lowering the risk of bleeding, and prevention of aspirin induced gastropathy.

Translated title of the contributionAntiaggregants in primary prevention of cardiovascular diseases and prevention of atherothrombosis in patients with stable ischemic heart disease: Aspects of efficacy and safety
Original languageRussian
Pages (from-to)55-67
Number of pages13
JournalКАРДИОЛОГИЯ
Volume58
Issue number2
DOIs
Publication statusPublished - 2018

Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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