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Research Output 1997 2020

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2020

Biological evaluation and molecular dynamics simulation of water-soluble fullerene derivative C60[C(COOH)2]3

Gaponenko, I. N., Ageev, S. V., Iurev, G. O., Shemchuk, O. S., Meshcheriakov, A. A., Petrov, A. V., Solovtsova, I. L., Vasina, L. V., Tennikova, T. B., Murin, I. V., Semenov, K. N. & Sharoyko, V. V., Feb 2020, In : Toxicology in Vitro. 62, 104683.

Research output

Open Access
Fullerenes
Molecular Dynamics Simulation
Molecular dynamics
Scavenging
Derivatives

Polythermal density and viscosity, nanoparticle size distribution, binding with human serum albumin and radical scavenging activity of the C60-L-arginine (C60(C6H13N4O2)8H8) aqueous solutions

Pochkaeva, E. I., Meshcheriakov, A. A., Ageev, S. V., Podolsky, N. E., Petrov, A. V., Charykov, N. A., Vasina, L. V., Nikolaeva, O. Y., Gaponenko, I. N., Sharoyko, V. V., Murin, I. V. & Semenov, K. N., 1 Jan 2020, In : Journal of Molecular Liquids. 297, 111915.

Research output

Arginine
Scavenging
scavenging
albumins
Serum Albumin
2019
4 Citations (Scopus)

1,2,4-Oxadiazole/2-Imidazoline Hybrids: Multi-target-directed Compounds for the Treatment of Infectious Diseases and Cancer

Shetnev, A., Baykov, S., Kalinin, S., Belova, A., Sharoyko, V., Rozhkov, A., Zelenkov, L., Tarasenko, M., Sadykov, E., Korsakov, M. & Krasavin, M., 1 Apr 2019, In : International Journal of Molecular Sciences. 20, 7, p. 1699 10 p., 1699.

Research output

Oxadiazoles
infectious diseases
Bacilli
Amides
Scaffolds
2 Citations (Scopus)
Piperidines
Nitrofurans
Multidrug-Resistant Tuberculosis
Mycobacterium tuberculosis
Retinal Pigments
1 Citation (Scopus)

Bioactivity study of the C 60 -L-threonine derivative for potential application in agriculture

Panova, G. G., Serebryakov, E. B., Semenov, K. N., Charykov, N. A., Shemchuk, O. S., Andrusenko, E. V., Kanash, E. V., Khomyakov, Y. V., Shpanev, A. M., Dulneva, L. L., Podolsky, N. E. & Sharoyko, V. V., 2019, In : Journal of Nanomaterials. 2019, 13 p., 2306518.

Research output

Open Access
Threonine
Pesticides
Bioactivity
Agriculture
Derivatives
10 Citations (Scopus)
Oxadiazoles
Carbonic Anhydrases
Sulfonamides
Protein Isoforms
Cells
1 Citation (Scopus)
Carbonic Anhydrases
Sulfonamides
Cytotoxicity
Glioma
Hydrogen
File
Pathogens
Cytotoxicity
Isomerization
Carboxylic Acids
Carboxylic acids
1 Citation (Scopus)
Thioredoxin Reductase 1
Lead compounds
Thioredoxins
Videodisks
Amides

Novel formulations of c-peptide with long-acting therapeutic potential for treatment of diabetic complications

Zashikhina, N., Sharoyko, V., Antipchik, M., Tarasenko, I., Anufrikov, Y., Lavrentieva, A., Tennikova, T. & Korzhikova-Vlakh, E., 1 Jan 2019, In : Pharmaceutics. 11, 1, 27.

Research output

Open Access
Nanospheres
Diabetes Complications
Phenylalanine
Peptides
C-Peptide
2 Citations (Scopus)
Open Access
Chitosan
Nanoparticles
Heparin
Epithelial Cells
Oligonucleotides
3 Citations (Scopus)
antioxidants
Antioxidants
Refraction
chemical properties
Chemical properties
3 Citations (Scopus)
Cells
Membranes
Cell Line
Protein Isoforms
Lead compounds
2018
3 Citations (Scopus)

Thermodynamic and thermal properties of the C60-L-Arg derivative

Semenov, K. N., Iurev, G. O., Pochkaeva, E. I., Lelet, M. I., Petrov, A. V., Charykov, N. A., Podolsky, N. E., Dulneva, L. L., Sharoyko, V. V. & Murin, I. V., 2018, In : Journal of Chemical Thermodynamics.

Research output

2017
11 Citations (Scopus)

Physico-chemical and biological properties of C60-l-hydroxyproline water solutions

Semenov, K. N., Meshcheriakov, A. A., Charykov, N. A., Dmitrenko, M. E., Keskinov, V. A., Murin, I. V., Panova, G. G., Sharoyko, V. V., Kanash, E. V. & Khomyakov, Y. V., 2017, In : RSC Advances. 7, p. 15189-15200

Research output

Physico-chemical and biological properties of C-60-L-hydroxyproline water solutions

Semenov, K. N., Meshcheriakov, A. A., Charykov, N. A., Dmitrenko, M. E., Keskinov, V. A., Murin, I. V., Panova, G. G., Sharoyko, V. V., Kanash, E. V. & Khomyakov, Y. V., 13 Feb 2017, In : RSC Advances. 7, 25, p. 15189-15200 12 p.

Research output

11 Citations (Scopus)

Physico-chemical properties of the C60 -L-lysine water solutions

Semenov, K. N., Charykov, N. A., Iurev, G. O., Ivanova, N. M., Keskinov, V. A., Letenko, D. G., Postnov, V. N., Sharoyko, V. V., Kulenova, N. A., Prikhodko, I. V. & Murin, I. V., 2017, In : Journal of Molecular Liquids. 225, 1, p. 767-777

Research output

lysine
chemical properties
Chemical properties
Lysine
conductivity
2 Citations (Scopus)

Pressure dependence of the solubility of light fullerenes in n-nonane

Semenov, K. N., Charykov, N. A., López, E. R., Fernández, J., Sharoyko, V. V. & Murin, I. V., 2017, In : Journal of Chemical Thermodynamics. 112, p. 259-266

Research output

9 Citations (Scopus)
Cysteine
Bearings (structural)
Nanoparticles
Peptides
Labels
2 Citations (Scopus)

Synthetic Route to 4,4a- and 3,4-Dihydroxanthones through [4+2] Cycloaddition and Base-Assisted Sigmatropic Rearrangement

Chernov, N. M., Shutov, R. V., Sharoyko, V. V., Kuz'mich, N. N., Belyakov, A. V. & Yakovlev, I. P., 1 Jan 2017, In : European Journal of Organic Chemistry. 2017, 19, p. 2836-2841 6 p.

Research output

Chromones
Lewis Acids
Cycloaddition
cycloaddition
Isomerization
2016
26 Citations (Scopus)

Fullerenols: Physicochemical properties and applications

Semenov, K. N., Charykov, N. A., Postnov, V. N., Sharoyko, V. V., Vorotyntsev, I. V., Galagudza, M. M. & Murin, I. V., 2016, In : Progress in Solid State Chemistry. 44, 2, p. 59-74 16 p.

Research output

Fullerenes
fullerenes
Derivatives
Water
synthesis
10 Citations (Scopus)

Precise expression of Fis1 is important for glucose responsiveness of beta cells

Schultz, J., Waterstradt, R., Kantowski, T., Rickmann, A., Reinhardt, F., Sharoyko, V., Mulder, H., Tiedge, M. & Baltrusch, S., 2016, In : Journal of Endocrinology.

Research output

9 Citations (Scopus)

Preparation, characterization, and biological evaluation of poly(glutamic acid)-b-polyphenylalanine polymersomes.

Vlakh, E., Ananyan, A., Zashikhina, N., Hubina, A., Pogodaev, A., Volokitina, M., Sharoyko, V. & Tennikova, T., 2016, In : Polymers. 8, p. 212

Research output

11 Citations (Scopus)
2015
35 Citations (Scopus)

Characterization of Stimulus-Secretion Coupling in the Human Pancreatic EndoC-βH1 Beta Cell Line.

Andersson, LE., Valtat, B., Bagge, A., Sharoyko, VV., Nicholls, DG., Ravassard, P., Scharfmann, R., Spégel, P. & Mulder, H., 2015, In : PLoS ONE. Mar 24;10(3):e0120879. doi: 10.1371/journal.pone.0120879. eCollection 2015.

Research output

Cells
cell lines
secretion
Cell Line
glucose
6 Citations (Scopus)

Inhibition of the malate-aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion.

Stamenkovic, JA., Andersson, LE., Adriaenssens, AE., Bagge, A., Sharoyko, VV., Gribble, F., Reimann, F., Wollheim, CB., Mulder, H. & Spégel, P., 2015, In : Biochemical Journal.

Research output

3 Citations (Scopus)

Lichens’ β-oligosaccharides in the correction of mеtаbolic disordersin type 2 diаbеtеs mellitus

Kershengolts, B. M., Sydykova, L. A., Sharoyko, V. V., Anshakova, V. V., Stepanova, A. V. & Varfolomeeva, N. A., 2015, In : Wiadomosci Lekarskie. 68, 4, p. 480-482

Research output

Lichens
Oligosaccharides
Dietary Supplements
Laboratory Chemicals
Hematologic Tests
15 Citations (Scopus)

Physico-chemical properties of the C<inf>60</inf>-arginine water solutions

Shestopalova, A. A., Semenov, K. N., Charykov, N. A., Postnov, V. N., Ivanova, N. M., Sharoyko, V. V., Keskinov, V. A., Letenko, D. G., Nikitin, V. A., Klepikov, V. V. & Murin, I. V., 2015, In : Journal of Molecular Liquids. p. 301-307

Research output

Arginine
chemical properties
Chemical properties
conductivity
Water

Physico-chemical properties of the C60-arginine water solutions

Shestopalova, A. A., Semenov, K. N., Charykov, N. A., Postnov, V. N., Ivanova, N. M., Sharoyko, V. V., Keskinov, V. A., Letenko, D. G., Nikitin, V. A., Klepikov, V. V. & Murin, I. V., 2015, In : Journal of Molecular Liquids. 211, p. 301-307

Research output

Arginine
chemical properties
Chemical properties
conductivity
Water
12 Citations (Scopus)

Physico-chemical properties of the water-soluble C<inf>70</inf>-tris-malonic solutions

Manyakina, O. S., Semenov, K. N., Charykov, N. A., Ivanova, N. M., Keskinov, V. A., Sharoyko, V. V., Letenko, D. G., Nikitin, V. A., Klepikov, V. V. & Murin, I. V., 2015, In : Journal of Molecular Liquids. p. 487-493

Research output

chemical properties
Chemical properties
Water
water
conductivity

Physico-chemical properties of the water-soluble C70-tris-malonic solutions

Manyakina, O. S., Semenov, K. N., Charykov, N. A., Ivanova, N. M., Keskinov, V. A., Sharoyko, V. V., Letenko, D. G., Nikitin, V. A., Murin, I. V. & Klepikov, V. V., 2015, In : Journal of Molecular Liquids. 21, p. 487–493

Research output

chemical properties
Chemical properties
Water
water
conductivity
10 Citations (Scopus)

Unique and Shared Metabolic Regulation in Clonal β-cells and Primary Islets Derived from Rat Revealed by Metabolomics Analysis.

Spégel, P., Andersson, LE., Storm, P., Sharoyko, V., Göhring, I., Rosengren, AH. & Mulder, H., 2015, In : Endocrinology.

Research output

Metabolomics
Islets of Langerhans
Glucose
Aminobutyrates
Glucose-6-Phosphate
2014
27 Citations (Scopus)
Pyruvic Acid
Gastrin-Secreting Cells
Energy Metabolism
Insulin
Glucose
16 Citations (Scopus)

Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin secretion and diabetes.

Sharoyko, VV., Abels, M., Sun, J., Nicholas, LM., Mollet, IG., Stamenkovic, JA., Göhring, I., Malmgren, S., Storm, P., Fadista, J., Spégel, P., Metodiev, MD., Larsson, NG., Eliasson, L., Wierup, N. & Mulder, H., 2014, In : Human Molecular Genetics. 23, 21, p. 5733-49.

Research output

Insulin
Mitochondrial Proteins
Type 2 Diabetes Mellitus
Secretory Vesicles
Medical Genetics
2013
6 Citations (Scopus)

The transcriptional co-repressor myeloid translocation gene 16 inhibits glycolysis and stimulates mitochondrial respiration.

Kumar, P., Sharoyko, VV., Spégel, P., Gullberg, U., Mulder, H., Olsson, I. & Ajore, R., 2013, In : PLoS ONE. 8, 7, p. e68502

Research output

Co-Repressor Proteins
glycolysis
Glycolysis
pyruvate dehydrogenase (acetyl-transferring) kinase
cell respiration
42 Citations (Scopus)

Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release.

Spégel, P., Sharoyko, VV., Goehring, I., Danielsson, AP., Malmgren, S., Nagorny, CL., Andersson, LE., Koeck, T., Sharp, GW., Straub, SG., Wollheim, CB. & Mulder, H., 2013, In : Biochemical Journal. 450, 3, p. 595-605.

Research output

Pentoses
Pentose Phosphate Pathway
Metabolomics
Metabolites
NADP
2011
31 Citations (Scopus)
Metabolomics
Citric Acid Cycle
Metabolism
Cells
Insulin

Зачем нужны и что могут дать биотехнологии российскому Северу.

Кершенгольц, Б., Ремигайло, П., Хлебный, Е., Шаройко, В., Шеин, А., Шашурин, М., Филиппова, Г., Журавская, А. & Аньшакова, В., 2011, In : НАУКА ИЗ ПЕРВЫХ РУК. 1, p. 48-60

Research output

2010

Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells.

Krus, U., Kotova, O., Spégel, P., Hallgard, E., Sharoyko, VV., Vedin, A., Moritz, T., Sugden, MC., Koeck, T. & Mulder, H., 2010, In : Biochemical Journal. 429, 1, p. 205-13.

Research output