Research Output 2002 2019

2019

1,2,4-Oxadiazole/2-Imidazoline Hybrids: Multi-target-directed Compounds for the Treatment of Infectious Diseases and Cancer

Shetnev, A., Baykov, S., Kalinin, S., Belova, A., Sharoyko, V., Rozhkov, A., Zelenkov, L., Tarasenko, M., Sadykov, E., Korsakov, M. & Krasavin, M., 1 Apr 2019, In : International Journal of Molecular Sciences. 20, 7, p. 1699 10 p., 1699.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A three-component, Zn(OTf)2-mediated entry into trisubstituted 2-aminoimidazoles

Lukin, A., Bakholdina, A., Kryukova, A., Sapegin, A. & Krasavin, M., 1 Jan 2019, In : Beilstein Journal of Organic Chemistry. 15, p. 1061-1064 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Attachment of a 5-nitrofuroyl moiety to spirocyclic piperidines produces non-toxic nitrofurans that are efficacious in vitro against multidrug-resistant Mycobacterium tuberculosis

Krasavin, M., Lukin, A., Vedekhina, T., Manicheva, O., Dogonadze, M., Vinogradova, T., Zabolotnykh, N., Rogacheva, E., Kraeva, L., Sharoyko, V., Tennikova, T. B., Dar'in, D. & Sokolovich, E., 15 Mar 2019, In : European Journal of Medicinal Chemistry. 166, p. 125-135 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Biocompatible zinc(II) 8-(dihydroimidazolyl)quinoline complex and its catalytic application for synthesis of poly(L,L-lactide)

Bolotin, D. S., Korzhikov-Vlakh, V., Sinitsyna, E., Yunusova, S. N., Suslonov, V. V., Shetnev, A., Osipyan, A., Krasavin, M. & Kukushkin, V. Y., 1 Apr 2019, In : Journal of Catalysis. 372, p. 362-369 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Continued exploration of 1,2,4-oxadiazole periphery for carbonic anhydrase-targeting primary arene sulfonamides: Discovery of subnanomolar inhibitors of membrane-bound hCA IX isoform that selectively kill cancer cells in hypoxic environment

Krasavin, M., Shetnev, A., Sharonova, T., Baykov, S., Kalinin, S., Nocentini, A., Sharoyko, V., Poli, G., Tuccinardi, T., Presnukhina, S., Tennikova, T. B. & Supuran, C. T., 15 Feb 2019, In : European Journal of Medicinal Chemistry. 164, p. 92-105 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Design, synthesis, and biological evaluation of novel derivatives of dithiodiglycolic acid prepared via oxidative coupling of thiols

Bakulina, O., Bannykh, A., Jovanović, M., Domračeva, I., Podolski-Renić, A., Žalubovskis, R., Pešić, M., Dar’in, D. & Krasavin, M., 1 Jan 2019, In : Journal of Enzyme Inhibition and Medicinal Chemistry. 34, 1, p. 665-671 7 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Effect of chiral polyhydrochromenes on cannabinoid system

Li-Zhulanov, N. S., Il’ina, I. V., Chicca, A., Schenker, P., Patrusheva, O. S., Nazimova, E. V., Korchagina, D. V., Krasavin, M., Volcho, K. P. & Salakhutdinov, N. F., 1 Jan 2019, In : Medicinal Chemistry Research.

Research output: Contribution to journalArticleResearchpeer-review

Facile access to Fe(III)-complexing cyclic hydroxamic acids in a three-component format

Chupakhin, E., Bakulina, O., Dar’in, D. & Krasavin, M., 1 Mar 2019, In : Molecules. 24, 5, 15 p., 864.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

New crystal forms for biologically active compounds. Part 1: Noncovalent interactions in adducts of nevirapine with XB donors

Kryukova, M. A., Sapegin, A. V., Novikov, A. S., Krasavin, M. & Ivanov, D. M., 1 Feb 2019, In : Crystals. 9, 2, 71.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Non-chelating p-phenylidene-linked bis-imidazoline analogs of known influenza virus endonuclease inhibitors: Synthesis and anti-influenza activity

Dar'in, D., Zarubaev, V., Galochkina, A., Gureev, M. & Krasavin, M., 1 Jan 2019, In : European Journal of Medicinal Chemistry. 161, p. 526-532 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Pyridazinone-substituted benzenesulfonamides display potent inhibition of membrane-bound human carbonic anhydrase IX and promising antiproliferative activity against cancer cell lines

Krasavin, M., Shetnev, A., Baykov, S., Kalinin, S., Nocentini, A., Sharoyko, V., Poli, G., Tuccinardi, T., Korsakov, M., Tennikova, T. B. & Supuran, C. T., 15 Apr 2019, In : European Journal of Medicinal Chemistry. 168, p. 301-314 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
2 Citations (Scopus)

Rh(II)-Catalyzed spirocyclization of α-diazo homophthalimides with cyclic ethers

Guranova, N. I., Dar’in, D., Kantin, G., Novikov, A. S., Bakulina, O. & Krasavin, M., 5 Apr 2019, In : The Journal of organic chemistry. 84, 7, p. 4534-4542 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of various arylated trifluoromethyl substituted indanes and indenes, and study of their biological activity

Iakovenko, R. O., Chicca, A., Nieri, D., Reynoso-Moreno, I., Gertsch, J., Krasavin, M. & Vasilyev, A. V., 1 Feb 2019, In : Tetrahedron. 75, 5, p. 624-632 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The use of ∝-diazo-γ-butyrolactone in the Büchner-Curtius-Schlotterbeck reaction of cyclic ketones: A facile entry into spirocyclic scaffolds

Shershnev, I., Dar'in, D. V., Chuprun, S. S., Kantin, G. P., Bakulina, O. Y. & Krasavin, M., 4 Jul 2019, In : Tetrahedron Letters. 60, 27, p. 1800-1802 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Three-Component Castagnoli-Cushman Reaction of 3-Arylglutaconic Acids with Aromatic Aldehydes and Amines Delivers Rare 4,6-Diaryl-1,6-dihydropyridin-2(3 H)-ones

Firsov, A., Chupakhin, E., Dar'In, D., Bakulina, O. & Krasavin, M., 15 Mar 2019, In : Organic Letters. 21, 6, p. 1637-1640 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Zn(OTf)2-catalyzed, microwave-promoted synthesis of 2-substituted 5-methyloxazoles from propargylic amides

Safrygin, A., Dar'in, D., Lukin, A., Bakholdina, A., Sapegin, A. & Krasavin, M., 1 Jan 2019, (Accepted/In press) In : Tetrahedron Letters.

Research output: Contribution to journalArticleResearchpeer-review

2018
2 Citations (Scopus)

1,4-Diiodo-2,3,5,6-tetrafluorobenzene (DITFB) in the synthesis of polyfluorinated organic compounds

Sapegin, A. & Krasavin, M., 1 May 2018, In : Journal of Fluorine Chemistry. 209, p. 56-64 9 p.

Research output: Contribution to journalReview articleResearchpeer-review

7 Citations (Scopus)

Achievements in the synthesis of cyclooctynes for ring strain-promoted [3+2] azide-alkyne cycloaddition

Chupakhin, E. G. & Krasavin, M. Y., 1 May 2018, In : Chemistry of Heterocyclic Compounds. 54, 5, p. 483-501 19 p.

Research output: Contribution to journalReview articleResearchpeer-review

1 Citation (Scopus)

Aldazines in the Castagnoli-Cushman Reaction

Mikheyev, A., Kantin, G. & Krasavin, M., 17 May 2018, In : Synthesis (Germany). 50, 10, p. 2076-2086 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Bicyclic Piperazine Mimetics of the Peptide β-Turn Assembled via the Castagnoli-Cushman Reaction

Usmanova, L., Dar'In, D., Novikov, M. S., Gureev, M. & Krasavin, M., 18 May 2018, In : Journal of Organic Chemistry. 83, 10, p. 5859-5868 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Concise synthesis of 2-N-hydroxy-3,4-dihydroisoquinol-2-one: A bacterial siderophore and human 5-lipooxygenase inhibitor

Tutov, A., Bakulina, O., Dar'in, D. & Krasavin, M., 11 Apr 2018, In : Tetrahedron Letters. 59, 15, p. 1511-1512 2 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Conjugation of a 5-nitrofuran-2-oyl moiety to aminoalkylimidazoles produces non-toxic nitrofurans that are efficacious in vitro and in vivo against multidrug-resistant Mycobacterium tuberculosis

Krasavin, M., Lukin, A., Vedekhina, T., Manicheva, O., Dogonadze, M., Vinogradova, T., Zabolotnykh, N., Rogacheva, E., Kraeva, L. & Yablonsky, P., 5 Sep 2018, In : European Journal of Medicinal Chemistry. 157, p. 1115-1126 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Discovery of polar spirocyclic orally bioavailable urea inhibitors of soluble epoxide hydrolase

Lukin, A., Kramer, J., Hartmann, M., Weizel, L., Hernandez-Olmos, V., Falahati, K., Burghardt, I., Kalinchenkova, N., Bagnyukova, D., Zhurilo, N., Rautio, J., Forsberg, M., Ihalainen, J., Auriola, S., Leppänen, J., Konstantinov, I., Pogoryelov, D., Proschak, E., Dar'in, D. & Krasavin, M., 1 Oct 2018, In : Bioorganic Chemistry. 80, p. 655-667 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Diversity-oriented synthesis of N,N-dimethylamino-substituted azoles employing TBTU

Lukin, A., Kalinchenkova, N., Vedekhina, T., Zhurilo, N. & Krasavin, M., 11 Jul 2018, In : Tetrahedron Letters. 59, 28, p. 2732-2735 4 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Efficient Conversion of Tertiary Propargylamides into Imidazoles via Hydroamination-Cyclization

Safrygin, A., Krivosheyeva, E., Dar'in, D. & Krasavin, M., 1 Aug 2018, In : Synthesis (Germany). 50, 15, p. 3048-3058 11 p., ss-2018-z0257-op.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Efficient Suzuki-Miyaura mono-arylation of symmetrical diiodo(hetero)arenes

Sapegin, A. & Krasavin, M., 16 May 2018, In : Tetrahedron Letters. 59, 20, p. 1948-1951 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Extraction of actinides with heterocyclic dicarboxamides

Alyapyshev, M., Babain, V., Tkachenko, L., Kenf, E., Voronaev, I., Dar’in, D., Matveev, P., Petrov, V., Kalmykov, S. & Ustynyuk, Y., 1 May 2018, In : Journal of Radioanalytical and Nuclear Chemistry. 316, 2, p. 419-428 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Facile Access to 3-Unsubstituted Tetrahydroisoquinolonic Acids via the Castagnoli-Cushman Reaction

Guranova, N., Dar'In, D. & Krasavin, M., 17 May 2018, In : Synthesis (Germany). 50, 10, p. 2001-2008 8 p., ss-2017-t0751-op.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Gold-Catalyzed Hydrohydrazidation of Terminal Alkynes

Zimin, D. P., Dar'In, D. V., Rassadin, V. A. & Kukushkin, V. Y., 17 Aug 2018, In : Organic Letters. 20, 16, p. 4880-4884 5 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Heterocyclic periphery in the design of carbonic anhydrase inhibitors: 1,2,4-Oxadiazol-5-yl benzenesulfonamides as potent and selective inhibitors of cytosolic hCA II and membrane-bound hCA IX isoforms

Krasavin, M., Shetnev, A., Sharonova, T., Baykov, S., Tuccinardi, T., Kalinin, S., Angeli, A. & Supuran, C. T., 1 Feb 2018, In : Bioorganic Chemistry. 76, p. 88-97 10 p.

Research output: Contribution to journalArticleResearchpeer-review

How to avoid protein aggregation to improve cellular uptake of albumin-based conjugates: towards the rational design of cell-penetrable phosphorescent probes

Соломатина, А. И., Байгильдин, В. А., Жуковский, Д. Д., Крупеня, Д. В., Кошель, Е. И., Щеславский, В. И., Туник, С. П. & Челушкин, П. С., 18 Oct 2018, In : Colloid and Polymer Science.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Mixed carboxylic-sulfonic anhydride in reaction with imines: a straightforward route to water-soluble beta-lactams via a Staudinger-type reaction

Bakulina, O., Dar'in, D. & Krasavin, M., 7 Jun 2018, In : Organic and Biomolecular Chemistry. 16, 21, p. 3989-3998 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Modern Trends of Organic Chemistry in Russian Universities

Konovalov, A. I., Antipin, I. S., Burilov, V. A., Madzhidov, T. I., Kurbangalieva, A. R., Nemtarev, A. V., Solovieva, S. E., Stoikov, I. I., Mamedov, V. A., Zakharova, L. Y., Gavrilova, E. L., Sinyashin, O. G., Balova, I. A., Vasilyev, A. V., Zenkevich, I. G., Krasavin, M. Y., Kuznetsov, M. A., Molchanov, A. P., Novikov, M. S., Nikolaev, V. A. & 59 othersRodina, L. L., Khlebnikov, A. F., Beletskaya, I. P., Vatsadze, S. Z., Gromov, S. P., Zyk, N. V., Lebedev, A. T., Lemenovskii, D. A., Petrosyan, V. S., Nenaidenko, V. G., Negrebetskii, V. V., Baukov, Y. I., Shmigol’, T. A., Korlyukov, A. A., Tikhomirov, A. S., Shchekotikhin, A. E., Traven’, V. F., Voskresenskii, L. G., Zubkov, F. I., Golubchikov, O. A., Semeikin, A. S., Berezin, D. B., Stuzhin, P. A., Filimonov, V. D., Krasnokutskaya, E. A., Fedorov, A. Y., Nyuchev, A. V., Orlov, V. Y., Begunov, R. S., Rusakov, A. I., Kolobov, A. V., Kofanov, E. R., Fedotova, O. V., Egorova, A. Y., Charushin, V. N., Chupakhin, O. N., Klimochkin, Y. N., Osyanin, V. A., Reznikov, A. N., Fisyuk, A. S., Sagitullina, G. P., Aksenov, A. V., Aksenov, N. A., Grachev, M. K., Maslennikova, V. I., Koroteev, M. P., Brel’, A. K., Lisina, S. V., Medvedeva, S. M., Shikhaliev, K. S., Suboch, G. A., Tovbis, M. S., Mironovich, L. M., Ivanov, S. M., Kurbatov, S. V., Kletskii, M. E., Burov, O. N., Kobrakov, K. I. & Kuznetsov, D. N., 1 Feb 2018, In : Russian Journal of Organic Chemistry. 54, 2, p. 157-371 215 p.

Research output: Contribution to journalReview articleResearchpeer-review

2 Citations (Scopus)

Novel monoamine oxidase inhibitors based on the privileged 2-imidazoline molecular framework

Shetnev, A., Osipyan, A., Baykov, S., Sapegin, A., Chirkova, Z., Korsakov, M., Petzer, A., Engelbrecht, I. & Petzer, J. P., 2018, In : Bioorganic and Medicinal Chemistry Letters. 29, 1, p. 40-46

Research output: Contribution to journalArticleResearchpeer-review

Open Access
5 Citations (Scopus)

Rare Medium-Sized Rings Prepared via Hydrolytic Imidazoline Ring Expansion (HIRE)

Osipyan, A., Sapegin, A., Novikov, A. S. & Krasavin, M., 13 Aug 2018, In : Journal of Organic Chemistry. 83, 17, p. 9707-9717

Research output: Contribution to journalArticleResearchpeer-review

Synthesis and medicinal applications of n-aryl-c-nitroazoles

Chuprun, S. S., Kantin, G. & Krasavin, M., 1 Jan 2018, In : Mini-Reviews in Medicinal Chemistry. 18, 20, p. 1733-1752 20 p.

Research output: Contribution to journalReview articleResearchpeer-review

2 Citations (Scopus)

The Castagnoli-Cushman reaction in a three-component format

Chupakhin, E., Dar'in, D. & Krasavin, M., 27 Jun 2018, In : Tetrahedron Letters. 59, 26, p. 2595-2599 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The First Example of Azole-Fused Cyclic Anhydride Reacting in the Castagnoli-Cushman Way

Moreau, E., Dar'In, D. & Krasavin, M., 23 Apr 2018, In : Synlett. 29, 7, p. 890-893 4 p., st-2017-b0833-l.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Unprotected primary sulfonamide group facilitates ring-forming cascade en route to polycyclic [1,4]oxazepine-based carbonic anhydrase inhibitors

Sapegin, A., Kalinin, S., Angeli, A., Supuran, C. T. & Krasavin, M., 1 Feb 2018, In : Bioorganic Chemistry. 76, p. 140-146 7 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Unusually Reactive Cyclic Anhydride Expands the Scope of the Castagnoli-Cushman Reaction

Chizhova, M., Khoroshilova, O., Dar'In, D. & Krasavin, M., 18 Sep 2018, In : Journal of Organic Chemistry.

Research output: Contribution to journalArticleResearchpeer-review